RBZ

ALPHA-RIBAZOLE-5'-PHOSPHATE

Created:	2002-03-19
Last modified:	2011-06-04

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4 entries where RBZ is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	43
Chiral Atom Count	4
Bond Count	45
Aromatic Bond Count	10

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Chemical Component Summary
Name	ALPHA-RIBAZOLE-5'-PHOSPHATE
Systematic Name (OpenEye OEToolkits)	[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-3,4-dihydroxy-oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₄ H₁₉ N₂ O₇ P
Molecular Weight	358.284
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OCC3OC(n2cnc1cc(c(cc12)C)C)C(O)C3O
SMILES	CACTVS	3.341	Cc1cc2ncn([CH]3O[CH](CO[P](O)(O)=O)[CH](O)[CH]3O)c2cc1C
SMILES	OpenEye OEToolkits	1.5.0	Cc1cc2c(cc1C)n(cn2)C3C(C(C(O3)COP(=O)(O)O)O)O
Canonical SMILES	CACTVS	3.341	Cc1cc2ncn([C@H]3O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]3O)c2cc1C
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1cc2c(cc1C)n(cn2)[C@@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O
InChI	InChI	1.03	InChI=1S/C14H19N2O7P/c1-7-3-9-10(4-8(7)2)16(6-15-9)14-13(18)12(17)11(23-14)5-22-24(19,20)21/h3-4,6,11-14,17-18H,5H2,1-2H3,(H2,19,20,21)/t11-,12-,13-,14+/m1/s1
InChIKey	InChI	1.03	ZMRGXEJKZPRBPJ-SYQHCUMBSA-N

Drug Info: DrugBank

DrugBank ID	DB02030
Name	Alpha-Ribazole-5'-Phosphate
Groups	experimental
Synonyms	Alpha-Ribazole-5'-Phosphate

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	MQTLHALLRDIPAPDAEAMARAQQHIDGLLKPPGSLGRLETLAVQLAGMP...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682