PMP

4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE

Created:	1999-07-08
Last modified:	2024-09-27

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120 entries where PMP is found as a standalone ligand7 entries where PMP is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	29
Chiral Atom Count	0
Bond Count	29
Aromatic Bond Count	6

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Chemical Component Summary
Name	4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE
Synonyms	PYRIDOXAMINE-5'-PHOSPHATE
Systematic Name (OpenEye OEToolkits)	[4-(aminomethyl)-5-hydroxy-6-methyl-pyridin-3-yl]methyl dihydrogen phosphate
Formula	C₈ H₁₃ N₂ O₅ P
Molecular Weight	248.173
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OCc1cnc(c(O)c1CN)C
SMILES	CACTVS	3.341	Cc1ncc(CO[P](O)(O)=O)c(CN)c1O
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(c(c(cn1)COP(=O)(O)O)CN)O
Canonical SMILES	CACTVS	3.341	Cc1ncc(CO[P](O)(O)=O)c(CN)c1O
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(c(c(cn1)COP(=O)(O)O)CN)O
InChI	InChI	1.03	InChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
InChIKey	InChI	1.03	ZMJGSOSNSPKHNH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB02142
Name	Pyridoxamine-5'-Phosphate
Groups	experimental
Synonyms	Pyridoxamine phosphate Pyridoxamine-5'-Phosphate
CAS number	529-96-4

Drug Targets

Name	Target Sequence	Pharmacological Action
Alanine racemase	MNDFHRDTWAEVDLDAIYDNVENLRRLLPDDTHIMAVVKANAYGHGDVQV...	unknown
Glutamate-1-semialdehyde 2,1-aminomutase	MVTSSPFKTIKSDEIFAAAQKLMPGGVSSPVRAFKSVGGQPIVFDRVKDA...	unknown
Histidinol-phosphate aminotransferase	MNPLDLIAKRAYPYETEKRDKTYLALNENPFPFPEDLVDEVFRRLNSDAL...	unknown
D-alanine aminotransferase	MGYTLWNDQIVKDEEVKIDKEDRGYQFGDGVYEVVKVYNGEMFTVNEHID...	unknown
Aspartate aminotransferase	MRGLSRRVQAMKPSATVAVNAKALELRRQGVDLVALTAGEPDFDTPEHVK...	unknown
4-aminobutyrate aminotransferase GabT	MNSNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYLDFAGGI...	unknown
Kynurenine--oxoglutarate transaminase 1	MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAF...	unknown
Histidinol-phosphate aminotransferase	MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFQLTQQ...	unknown
Branched-chain-amino-acid aminotransferase, mitochondrial	MAAAALGQIWARKLLSVPWLLCGPRRYASSSFKAADLQLEMTQKPHKKPG...	unknown
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase	MSDFLPFSRPAMGAEELAAVKTVLDSGWITTGPKNQELEAAFCRLTGNQY...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682