MET
METHIONINE
Find entries where: MET
is present as a standalone ligand in 200 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 29 entries
is present in a polymer sequence 204,826 entries
Chemical Component Summary | |
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Name | METHIONINE |
Identifiers | (2S)-2-amino-4-methylsulfanyl-butanoic acid |
Formula | C5 H11 N O2 S |
Molecular Weight | 149.211 |
Type | L-PEPTIDE LINKING |
Isomeric SMILES | CSCC[C@@H](C(=O)O)N |
InChI | InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1 |
InChIKey | FFEARJCKVFRZRR-BYPYZUCNSA-N |
Chemical Details | |
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Formal Charge | 0 |
Atom Count | 20 |
Chiral Atom Count | 1 |
Bond Count | 19 |
Aromatic Bond Count | 0 |
Drug Info: DrugBank
DrugBank ID | DB00134 |
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Name | Methionine |
Groups |
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Description | A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals. |
Synonyms |
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Brand Names |
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Indication | Used for protein synthesis including the formation of SAMe, L-homocysteine, L-cysteine, taurine, and sulfate. |
Categories |
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ATC-Code | V03AB26 |
CAS number | 63-68-3 |
Drug Targets
Name | Target Sequence | Pharmacological Action | Actions |
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Methionine synthase reductase | MGAASVRAGARLVEVALCSFTVTCLEVMRRFLLLYATQQGQAKAIAEEIC... | unknown | product of |
Methionine synthase | MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEH... | unknown | product of |
Methionine aminopeptidase 2 | MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA... | unknown | product of |
Betaine--homocysteine S-methyltransferase 1 | MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAV... | unknown | product of |
S-methylmethionine--homocysteine S-methyltransferase BHMT2 | MAPAGRPGAKKGILERLESGEVVIGDGSFLITLEKRGYVKAGLWTPEAVI... | unknown | product of |
View More |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
Resource Name | Reference |
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PubChem | 6137, 6992087 |
ChEMBL | CHEMBL42336 |
ChEBI | CHEBI:57844, CHEBI:16643 |
CCDC/CSD | METHCL01, BANPUC, WOYVIP, URODIP03, URODIP02, CONZIO01, VUQNAY, POVYOP, DLMETA08, DLMETA05, URODIP, FITLID, MOCXUX, METHCL, YUDDIM, LUDHEX, BERQIY, YIGMEI, FAPMAL, FAPMEP, VUQNAY01, BERNIV, FONJAU, ZATNUH, ZATJUD, ZATNOB, ZATJOX, DLMETA12, ZATMOA, ZATLUF |
COD | 2240074, 2205625, 7212710, 2008948 |