Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
LYS
L-Lysin
6-ammonio-L-norleucine
L-2,6-Diaminocaproic acid
(S)-2,6-diaminohexanoic acid
Lysine acetate
Lysine
(S)-α,ε-diaminocaproic acid
Lysine monohydrate
L-lys
Lysine acid
L-Lysine
Lysinum
Lysina
(S)-lysine
Lysine dihydrate
Lysine hydrochloride
Brand Names
Aminosyn 8.5%
Aminosyn II 8.5% Injection
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Aminosyn-PF
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Olimel 3.3% E
FreAmine HBC
Travasol Amino Acid Inj 5.5%
Smofkabiven Peripheral
Vamin N
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn 5%
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Novamine
Aminosyn II 8.5% With 50% Dextrose
Olimel 4.4% E
FreAmine III
Smofkabiven
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Olimel 5.7% E
Aminosyn 3.5% M
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Aminosyn II 5% Inj
HepatAmine
Travasol Amino Acid Inj 8.5%
Smofkabiven Extra Nitrogen
Travasol
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Xyzmune
TrophAmine
Olimel 7.6%
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Olimel 4.4%
Clinimix E
Primene 10%
Lysakare
8.5% Freamine III
Aminosyn II with Electrolytes
Nephramine Liq IV
Aminosyn II 10% With Electrolytes
Clinimix
Plenamine
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn HF
Kabiven
Primene
Olimel 5.7%
RenAmin
Aminosyn
20% Prosol
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Primene 10%-liq IV
Hepatasol
Premasol - sulfite-free (Amino Acid)
Aminosyn II with Electrolytes in Dextrose with Calcium
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn-PF 7%
Olimel 7.6% E
Vamin 18 Electrolyte-free
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
ProSol
Aminosyn 7%
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Travasol Inj Without Electrolytes 8.5%
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn II 7% With 50% Dextrose
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Renamin (amino Acids) Injection
Perikabiven
ProcalAmine
Effervescent Potassium Chloride
Travasol E
Aminosyn II 7% Injection
Aminosyn II and Dextrose
Aminosyn RF Injection
Periolimel 2.5% E
NephrAmine
Aminosyn 10% W Electrolytes
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Imubolic
Aminosyn Sulfite Free
Aminosyn II In Dextrose Injection
Clinisol
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Aminosyn 8.5% Injection With Electrolytes
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn II
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Travasol Inj Without Electrolytes 5.5%
Aminosyn II in Dextrose
Smofkabiven Electrolyte Free
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn II 7% With 10% Dextrose
Aminosyn RF
Nutrineal Pd4
Essepna
Synthamin
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn-PF 10%
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682