LNL

ALPHA-LINOLENIC ACID

Created: 2000-08-23
Last modified:  2011-06-04

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Chemical Details

Formal Charge0
Atom Count50
Chiral Atom Count0
Bond Count49
Aromatic Bond Count0
2D diagram of LNL
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Chemical Component Summary

NameALPHA-LINOLENIC ACID
Systematic Name (OpenEye OEToolkits)(9Z)-octadeca-9,12,15-trienoic acid
FormulaC18 H30 O2
Molecular Weight278.43
TypeNON-POLYMER

Chemical Descriptors

TypeProgram Version Descriptor
SMILESACDLabs10.04O=C(O)CCCCCCC\C=C/C\C=C/C\C=C/CC
SMILESCACTVS3.341CCC=CCC=CCC=CCCCCCCCC(O)=O
SMILESOpenEye OEToolkits1.5.0CCC=CCC=CCC=CCCCCCCCC(=O)O
Canonical SMILESCACTVS3.341 CC\C=C/C/C=C\C\C=C/CCCCCCCC(O)=O
Canonical SMILESOpenEye OEToolkits1.5.0 CCC=CCC=CC\C=C/CCCCCCCC(=O)O
InChIInChI1.03 InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-4,6-7,9-10H,2,5,8,11-17H2,1H3,(H,19,20)/b4-3-,7-6-,10-9-
InChIKeyInChI1.03 DTOSIQBPPRVQHS-PDBXOOCHSA-N

Drug Info: DrugBank

DrugBank IDDB00132 
Namealpha-Linolenic acid
Groups
  • approved
  • investigational
  • nutraceutical
DescriptionAlpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Synonyms
  • cis-delta(9,12,15)-Octadecatrienoic acid
  • cis,cis,cis-9,12,15-Octadecatrienoic acid
  • (9,12,15)-linolenic acid
  • α-linolenic acid
  • all-cis-9,12,15-Octadecatrienoic acid
Brand Names
  • HemeNatal OB plus DHA
  • Folcaps Care One
  • Cavan One
  • Folcaps Omega-3
  • Huile D'onagre Vitamin E
IndicationFor nutritional supplementation and for treating dietary shortage or imbalance.
Categories
  • Dietary Fats
  • Dietary Fats, Unsaturated
  • Dietary Supplements
  • Fats
  • Fatty Acids
CAS number463-40-1

Drug Targets

NameTarget SequencePharmacological ActionActions
Fatty acid desaturase 1MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTR...unknownligand
Fatty acid desaturase 2MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWS...unknownligand
Transient receptor potential cation channel subfamily V member 1MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLF...unknowninhibitor
Peroxisome proliferator-activated receptor alphaMVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFG...unknown
Bile acid receptorMVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQN...unknownagonist
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL8739
PubChem 5280934
ChEMBL CHEMBL8739
ChEBI CHEBI:27432