HFA

ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID

Created:	1999-07-08
Last modified:	2024-09-27

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5 entries where HFA is found as a standalone ligand3 entries where HFA is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	1
Bond Count	22
Aromatic Bond Count	6

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Chemical Component Summary
Name	ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID
Systematic Name (OpenEye OEToolkits)	(2S)-2-hydroxy-3-phenyl-propanoic acid
Formula	C₉ H₁₀ O₃
Molecular Weight	166.174
Type	L-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)C(O)Cc1ccccc1
SMILES	CACTVS	3.341	O[CH](Cc1ccccc1)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	c1ccc(cc1)CC(C(=O)O)O
Canonical SMILES	CACTVS	3.341	O[C@@H](Cc1ccccc1)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1ccc(cc1)C[C@@H](C(=O)O)O
InChI	InChI	1.03	InChI=1S/C9H10O3/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8,10H,6H2,(H,11,12)/t8-/m0/s1
InChIKey	InChI	1.03	VOXXWSYKYCBWHO-QMMMGPOBSA-N

Drug Info: DrugBank

DrugBank ID	DB02494
Name	(S)-3-phenyllactic acid
Groups	experimental
Synonyms	L-(−)-3-phenyllactic acid (S)-3-phenyllactic acid L-3-phenyllactic acid alpha-hydroxy-beta-phenyl-propionic acid L-β-phenyllactic acid L-beta-Phenyllactic acid
CAS number	20312-36-1

Drug Targets

Name	Target Sequence	Pharmacological Action
L-phenylalanine dehydrogenase	MSIDSALNWDGEMTVTRFDRETGAHFVIRLDSTQLGPAAGGTRAAQYSQL...	unknown
60S ribosomal protein L10-like	MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLGG...	unknown
60S ribosomal protein L13a	MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRN...	unknown
60S ribosomal protein L23	MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLN...	unknown
60S ribosomal protein L15	MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARR...	unknown
60S ribosomal protein L19	MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLI...	unknown
60S ribosomal protein L23a	MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPK...	unknown
Probable ribosome biogenesis protein RLP24	MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVR...	unknown
60S ribosomal protein L26-like 1	MKFNPFVTSDRSKNRKRHFNAPSHVRRKIMSSPLSKELRQKYNVRSMPIR...	unknown
60S ribosomal protein L8	MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIH...	unknown
60S ribosomal protein L37	MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWS...	unknown
60S ribosomal protein L3	MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYK...	unknown
60S ribosomal protein L11	MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVF...	unknown
NHP2-like protein 1	MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGI...	unknown
Carboxypeptidase A1	MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQL...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682