DTV

(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL

Created:	2004-06-18
Last modified:	2024-09-27

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25 entries where DTV is found as a standalone ligand8 entries where DTV is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	18
Chiral Atom Count	2
Bond Count	17
Aromatic Bond Count	0

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Chemical Component Summary
Name	(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
Systematic Name (OpenEye OEToolkits)	(2S,3S)-1,4-bis-sulfanylbutane-2,3-diol
Formula	C₄ H₁₀ O₂ S₂
Molecular Weight	154.251
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	SCC(O)C(O)CS
SMILES	CACTVS	3.341	O[CH](CS)[CH](O)CS
SMILES	OpenEye OEToolkits	1.5.0	C(C(C(CS)O)O)S
Canonical SMILES	CACTVS	3.341	O[C@H](CS)[C@H](O)CS
Canonical SMILES	OpenEye OEToolkits	1.5.0	C([C@H]([C@@H](CS)O)O)S
InChI	InChI	1.03	InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChIKey	InChI	1.03	VHJLVAABSRFDPM-QWWZWVQMSA-N

Drug Info: DrugBank

DrugBank ID	DB02184
Name	D-1,4-dithiothreitol
Groups	experimental
Description	A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. [PubChem]
Synonyms	D-DTT D-1,4-dithiothreitol D-threo-1,4-dimercapto-2,3-butanediol (2S,3S)-1,4-dimercaptobutane-2,3-diol

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
6,7-dimethyl-8-ribityllumazine synthase	MKGGAGVPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDD...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682