DCP

2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE

Created:	1999-07-08
Last modified:	2011-06-04

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176 entries where DCP is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	44
Chiral Atom Count	5
Bond Count	45
Aromatic Bond Count	0

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Chemical Component Summary
Name	2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE
Systematic Name (OpenEye OEToolkits)	[(2R,3S,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3-hydroxy-oxolan-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
Formula	C₉ H₁₆ N₃ O₁₃ P₃
Molecular Weight	467.157
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC2OC(N1C(=O)N=C(N)C=C1)CC2O
SMILES	CACTVS	3.341	NC1=NC(=O)N(C=C1)[CH]2C[CH](O)[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)O2
SMILES	OpenEye OEToolkits	1.5.0	C1C(C(OC1N2C=CC(=NC2=O)N)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O
Canonical SMILES	CACTVS	3.341	NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO[P@](O)(=O)O[P@](O)(=O)O[P](O)(O)=O)O2
Canonical SMILES	OpenEye OEToolkits	1.5.0	C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO[P@@](=O)(O)O[P@@](=O)(O)OP(=O)(O)O)O
InChI	InChI	1.03	InChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
InChIKey	InChI	1.03	RGWHQCVHVJXOKC-SHYZEUOFSA-N

Drug Info: DrugBank

DrugBank ID	DB03258
Name	2'-Deoxycytidine 5'-triphosphate
Groups	experimental
Synonyms	2'-Deoxycytidine 5'-triphosphate Deoxycytidine 5'-triphosphate 2'-Deoxycytidine-5'-Triphosphate Deoxycytidine triphosphate dCTP
Categories	Cytosine Nucleotides Deoxyribonucleotides Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Pyrimidine Nucleotides Pyrimidines
CAS number	2056-98-6

Drug Targets

Name	Target Sequence	Pharmacological Action
Anaerobic ribonucleoside-triphosphate reductase	MTIEKEIEGLIHKTNKDLLNENANKDSRVFPTQRDLMAGIVSKHIAKNMV...	unknown
Deoxycytidine triphosphate deaminase	MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAA...	unknown
DNA polymerase I, thermostable	MRGMLPLFEPKGRVLLVDGHHLAYRTFHALKGLTTSRGEPVQAVYGFAKS...	unknown
Ribonucleoside-diphosphate reductase 2 subunit alpha	MATTTPERVMQETMDYHALNAMLNLYDKAGHIQFDKDQQAIDAFFATHVR...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682