DrugBank ID DB00205 Name Pyrimethamine Groups approved vet_approved investigational Description One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis. Synonyms 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine Diaminopyritamin Pirimetamina Chloridine Pyrimethaminum
5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine CD Ethylpyrimidine 2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine Pyriméthamine 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine Chloridyn Primethamine Pyrimethamine Pyrimethamine hydrochloride 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine more Brand Names Fansidar Tablets Fansidar Pyrimethamine Leucovorin Daraprim Pyrimethamine Indication For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine Categories Anti-Infective Agents Antibiotics for Pneumocystis Pneumonia Antimalarial diaminopyrimidines Antimalarials Antiparasitic Agents
Antiparasitic Products, Insecticides and Repellents Antiprotozoals Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors (weak) Cytochrome P-450 Enzyme Inhibitors Enzyme Inhibitors Folic Acid Antagonists MATE 1 Inhibitors MATE 2 Inhibitors MATE inhibitors Pyrimidines more ATC-Code P01BF09 P01BD01 P01BD51 P01BF04 CAS number 58-14-0 
