BFR

N-butyl-N'-(diaminomethylidene)guanidine

Created:	2017-01-19
Last modified:	2020-06-05

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1 entries where BFR is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	26
Chiral Atom Count	0
Bond Count	25
Aromatic Bond Count	0

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Chemical Component Summary
Name	N-butyl-N'-(diaminomethylidene)guanidine
Synonyms	Buformin
Systematic Name (OpenEye OEToolkits)	1-[bis(azanyl)methylidene]-3-butyl-guanidine
Formula	C₆ H₁₅ N₅
Molecular Weight	157.217
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	12.01	C(C)CCN\C(=N)\N=C(/N)N
SMILES	CACTVS	3.385	CCCCNC(=N)N=C(N)N
SMILES	OpenEye OEToolkits	2.0.6	CCCCNC(=N)N=C(N)N
Canonical SMILES	CACTVS	3.385	CCCCNC(=N)N=C(N)N
Canonical SMILES	OpenEye OEToolkits	2.0.6	[H]/N=C(\NCCCC)/N=C(N)N
InChI	InChI	1.03	InChI=1S/C6H15N5/c1-2-3-4-10-6(9)11-5(7)8/h2-4H2,1H3,(H6,7,8,9,10,11)
InChIKey	InChI	1.03	XSEUMFJMFFMCIU-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB04830
Name	Buformin
Groups	withdrawn investigational
Description	Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of causing lactic acidosis.
Synonyms	Buformin Buformin hydrochloride Buforminum Buformina Buformine 1-Butylbiguanide
Categories	Alimentary Tract and Metabolism Amidines Biguanides Blood Glucose Lowering Agents Drugs Used in Diabetes Guanidines OCT1 substrates Oral Hypoglycemics
ATC-Code	A10BA03
CAS number	692-13-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682