ACA

6-AMINOHEXANOIC ACID

Created:	1999-07-08
Last modified:	2024-09-27

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20 entries where ACA is found as a standalone ligand10 entries where ACA is covalently linked to polymer or other heterogen groups 29 entries where ACA is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	0

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Chemical Component Summary
Name	6-AMINOHEXANOIC ACID
Synonyms	AMINOCAPROIC ACID
Systematic Name (OpenEye OEToolkits)	6-aminohexanoic acid
Formula	C₆ H₁₃ N O₂
Molecular Weight	131.173
Type	PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)CCCCCN
SMILES	CACTVS	3.341	NCCCCCC(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(CCC(=O)O)CCN
Canonical SMILES	CACTVS	3.341	NCCCCCC(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(CCC(=O)O)CCN
InChI	InChI	1.03	InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChIKey	InChI	1.03	SLXKOJJOQWFEFD-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB00513
Name	Aminocaproic acid
Groups	approved investigational
Description	An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Synonyms	Epsilon-Aminocaproic acid acidum aminocaproicum omega-Aminocaproic acid Epsilcapramine Aminocapronsäure epsilon-Aminohexanoic acid Aminocaproic acid 6-aminohexanoic acid EACA omega-Aminohexanoic acid Epsilon Aminocaproic Acid Ácido aminocapróico 6-Aminocaproic acid Acide aminocaproïque EACS
Brand Names	NAVI Black and C-Clinic Greensaltrain Tooth Gray Salt Amicar Amicar Syr 250mg/ml Mastikis Mastic 24K Exoden White Tooth Mastikis Mastic GumCare Relief and Nature Toothpast E Jasmine Mint 28tak Gum Care Tooth Amicar - Syr 250mg/ml Solmeet BAMBOO SALT Eunganggo Jook Yeom Amicar Inj 250mg/ml HiMangChanToothpaste Solmeet denti doctor Amicar - Tab, 500mg Solco Platino Iondenti Tooth BAMBOO SALT Eunganggo Jook Yeom Toothpaste Aminocaproic Acid Hae Yan Tooth Amicar Tab 500mg Aminocaproic acid Gray Salt Tooth Saltrain Tooth Salt Tooth Dr.LORD Green Propol Tooth Yumaki Original Mint Tooth Dr.EL GUM CARE TOOTH Amicar Injection - Liq IV 250mg/ml Clean Breath Tooth Mastikis Gold Rootsallo Toothpaste LACSIAN new perfect all care tooth Hea YanToothpaste
Indication	For use in the treatment of excessive postoperative bleeding.
Categories	Acids, Acyclic Amino Acids Amino Acids, Peptides, and Proteins Aminocaproates Antifibrinolytic Agents Blood and Blood Forming Organs Caproates Coagulants Decreased Fibrinolysis Fibrin Modulating Agents Hematologic Agents Hemostatics
ATC-Code	B02AA01
CAS number	60-32-2

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Plasminogen	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECA...	unknown	inhibitor
Tissue-type plasminogen activator	MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIY...	unknown	antagonist
Apolipoprotein(a)	MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQ...	unknown	other
Aldehyde oxidase	MDRASELLFYVNGRKVIEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCG...	unknown	substrate

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL1046
PubChem	564, 517030
ChEMBL	CHEMBL1046
ChEBI	CHEBI:79212, CHEBI:57826, CHEBI:16586
CCDC/CSD	ZEMCIG, ZEMCEC, ZEMCAY, ZEMCUS, AMCAPR11, JIZHEF, EZOGAD, JIHFUE, QEGFIR, AMCAPR10, GAHHIK