2PG

2-PHOSPHOGLYCERIC ACID

Created:	1999-07-08
Last modified:	2011-06-04

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38 entries where 2PG is found as a standalone ligand3 entries where 2PG is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	18
Chiral Atom Count	1
Bond Count	17
Aromatic Bond Count	0

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Chemical Component Summary
Name	2-PHOSPHOGLYCERIC ACID
Systematic Name (OpenEye OEToolkits)	(2R)-3-hydroxy-2-phosphonooxy-propanoic acid
Formula	C₃ H₇ O₇ P
Molecular Weight	186.057
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OC(C(=O)O)CO
SMILES	CACTVS	3.341	OC[CH](O[P](O)(O)=O)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(C(C(=O)O)OP(=O)(O)O)O
Canonical SMILES	CACTVS	3.341	OC[C@@H](O[P](O)(O)=O)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C([C@H](C(=O)O)OP(=O)(O)O)O
InChI	InChI	1.03	InChI=1S/C3H7O7P/c4-1-2(3(5)6)10-11(7,8)9/h2,4H,1H2,(H,5,6)(H2,7,8,9)/t2-/m1/s1
InChIKey	InChI	1.03	GXIURPTVHJPJLF-UWTATZPHSA-N

Drug Info: DrugBank

DrugBank ID	DB01709
Name	2-phospho-D-glyceric acid
Groups	experimental
Description	A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration.
Synonyms	D-glycerate 2-phosphate 2-phospho-D-glyceric acid 2-phospho-D-glycerate

Drug Targets

Name	Target Sequence	Pharmacological Action
2-dehydro-3-deoxyphosphooctonate aldolase	MEKFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRS...	unknown
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	MSKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGE...	unknown
Triosephosphate isomerase	MARKYFVAANWKCNGTLESIKSLTNSFNNLDFDPSKLDVVVFPVSVHYDH...	unknown
Beta-enolase	MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELR...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682