8V2N
Human SIRT3 co-crystallized with ligands, including p53-AMC peptide and Carba-NAD
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF02146 | Sir2 family (SIR2) | Sir2 family | - | Family | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
NAD-dependent protein deacetylase sirtuin-3, mitochondrial | |
| ||
GLN-PRO-LYS-FDL | - | - | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR026590 | Sirtuin family, catalytic core domain | Domain | |
IPR003000 | Sirtuin family | Family | |
IPR029035 | DHS-like NAD/FAD-binding domain superfamily | Homologous Superfamily | |
IPR050134 | NAD-dependent sirtuin protein deacylases | Family | |
IPR026591 | Sirtuin, catalytic core small domain superfamily | Homologous Superfamily |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target | Associated Disease |
---|---|---|
Q9NTG7 | :