8RE7

Aspartyl/Asparaginyl beta-hydroxylase (AspH) R735W variant in complex with Mn, 2-oxoglutarate and a Factor X derived peptide fragment


Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF13432Tetratricopeptide repeat (TPR_16)Tetratricopeptide repeat- Repeat
PF05118Aspartyl/Asparaginyl beta-hydroxylase (Asp_Arg_Hydrox)Aspartyl/Asparaginyl beta-hydroxylaseIron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyse oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalysing oxidation of a free alpha-amino a ...Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Aspartyl/asparaginyl beta-hydroxylase
Coagulation factor X

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
PharosQ12797
PharosP00742