Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad6puja2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad6puja1 Alpha and beta proteins (a+b) MHC antigen-recognition domain MHC antigen-recognition domain automated matches automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad6puja3 Artifacts Tags Tags Tags N-terminal Tags Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd6pujc2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd6pujc1 Alpha and beta proteins (a+b) MHC antigen-recognition domain MHC antigen-recognition domain automated matches automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd6pujc3 Artifacts Tags Tags Tags N-terminal Tags Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd6pujb2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd6pujb1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Dd6pujd2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Dd6pujd1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ed6puje1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Gd6pujg1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Hd6pujh_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) beta2-microglobulin Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Fd6pujf_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) beta2-microglobulin Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
HSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8003766 3000071 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8003766 3000071 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AC1-set_2e6pujA2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
AMHC_Ie6pujA1 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_IECOD (1.6)
CC1-set_2e6pujC1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
CMHC_Ie6pujC2 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_IECOD (1.6)
BDUF1968e6pujB2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF1968ECOD (1.6)
BV-set_3e6pujB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
DDUF1968e6pujD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF1968ECOD (1.6)
DV-set_3e6pujD2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
EC1-sete6pujE2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-setECOD (1.6)
EV-set_3e6pujE1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
GC1-sete6pujG1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-setECOD (1.6)
GV-set_3e6pujG2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
HC1-set_2e6pujH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
FC1-set_2e6pujF1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
A, C
MR1 (5-OP-RU antigen) I-ALPHA-LIKE Homo sapiens (human) MR1*01 G-DOMAIN G-ALPHA1-LIKE, G-DOMAIN G-ALPHA2-LIKE, C-LIKE-DOMAIN C-LIKE RPI-MH1Like MH1LIKE-ALPHA-LIKE_B2M IMGT (202448-0)
B, D
TR MAIT A-F7 TR-ALPHA Homo sapiens (human) TRAV1-2*01, TRAV1-2*03, TRAJ33*01, TRAC*01 V-DOMAIN V-ALPHA, C-DOMAIN C-ALPHA TR TR-ALPHA_BETA-2 IMGT (202448-0)
E, G
TR MAIT A-F7 TR-BETA-2 Homo sapiens (human) TRBV6-1*01, TRBJ2-2*01, TRBC2*01, TRBC2*02 V-DOMAIN V-BETA, C-DOMAIN C-BETA-2 TR TR-ALPHA_BETA-2 IMGT (202448-0)
F, H
MR1 (5-OP-RU antigen) B2M Homo sapiens (human) B2M*01, B2M*02 C-LIKE-DOMAIN C-LIKE RPI-MH1Like MH1LIKE-ALPHA-LIKE_B2M IMGT (202448-0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C
PF00129Class I Histocompatibility antigen, domains alpha 1 and 2 (MHC_I)Class I Histocompatibility antigen, domains alpha 1 and 2- Domain
A, C
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
F, H
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, C
Major histocompatibility complex class I-related gene protein
B, D
Human TCR alpha chain---
E, G
Human TCR beta chain---
F, H
Beta-2-microglobulin

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, C
PharosQ95460
F, H
PharosP61769