5H8J

Crystal structure of Medicago truncatula N-carbamoylputrescine amidohydrolase (MtCPA) in complex with cadaverine

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d5h8jb_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
G	d5h8jg_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
M	d5h8jm_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
N	d5h8jn_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
A	d5h8ja_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
C	d5h8jc_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
D	d5h8jd_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
E	d5h8je_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
F	d5h8jf_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
H	d5h8jh_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
I	d5h8ji_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
J	d5h8jj_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
K	d5h8jk_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
L	d5h8jl_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
O	d5h8jo_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)
P	d5h8jp_	Alpha and beta proteins (a+b)	Carbon-nitrogen hydrolase	Carbon-nitrogen hydrolase	automated matches	automated matches	Barrel medic (Medicago truncatula ) [TaxId: 3880 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
O	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)
P	SCOP2B Superfamily	Carbon-nitrogen hydrolases	8081722	3001086	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	CN_hydrolase	e5h8jB1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
G	CN_hydrolase	e5h8jG1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
M	CN_hydrolase	e5h8jM1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
N	CN_hydrolase	e5h8jN1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
A	CN_hydrolase	e5h8jA1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
C	CN_hydrolase	e5h8jC1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
D	CN_hydrolase	e5h8jD1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
E	CN_hydrolase	e5h8jE1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
F	CN_hydrolase	e5h8jF1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
H	CN_hydrolase	e5h8jH1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
I	CN_hydrolase	e5h8jI1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
J	CN_hydrolase	e5h8jJ1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
K	CN_hydrolase	e5h8jK1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
L	CN_hydrolase	e5h8jL1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
O	CN_hydrolase	e5h8jO1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)
P	CN_hydrolase	e5h8jP1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Carbon-nitrogen hydrolase (From Topology)	T: Carbon-nitrogen hydrolase	F: CN_hydrolase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
G	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
M	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
N	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
A	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
C	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
D	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
E	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
F	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
H	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
I	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
J	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
K	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
L	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
O	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)
P	3.60.110.10	Alpha Beta	4-Layer Sandwich	Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase	Carbon-nitrogen hydrolase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	PF00795	Carbon-nitrogen hydrolase (CN_hydrolase)	Carbon-nitrogen hydrolase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	N-carbamoylputrescine amidohydrolase	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides hydrolase activity N-carbamoylputrescine amidase activity catalytic activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	oxoacid metabolic process carboxylic acid metabolic process amino acid metabolic process primary metabolic process organic acid metabolic process polyamine metabolic process alpha-amino acid metabolic process arginine metabolic process putrescine biosynthetic process amine metabolic process biogenic amine biosynthetic process biosynthetic process amine biosynthetic process polyamine biosynthetic process putrescine biosynthetic process from arginine oxoacid metabolic process carboxylic acid metabolic process amino acid metabolic process primary metabolic process organic acid metabolic process polyamine metabolic process alpha-amino acid metabolic process arginine metabolic process putrescine biosynthetic process amine metabolic process biogenic amine biosynthetic process biosynthetic process amine biosynthetic process polyamine biosynthetic process putrescine biosynthetic process from arginine putrescine metabolic process metabolic process cellular process small molecule metabolic process biogenic amine metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR036526	Carbon-nitrogen hydrolase superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR017755	N-carbamoylputrescine amidase	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR050345	Aliphatic Amidase/Beta-Ureidopropionase	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P	IPR003010	Carbon-nitrogen hydrolase	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.