5BQP

Hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT) from Sulfolobus solfataricus with xanthosine and phosphate bound in the nucleotide binding site and with sulfate bound in the pyrophosphate binding site

External Resource: Annotation


Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyPRTase-like 8065684 3000060 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyPRTase-like 8065684 3000060 SCOP2B (2022-06-29)
CSCOP2 FamilyPhosphoribosyltransferases (PRTases) 8065683 4000253 SCOP2 (2022-06-29)
CSCOP2 SuperfamilyPRTase-like 8065684 3000060 SCOP2 (2022-06-29)
DSCOP2B SuperfamilyPRTase-like 8065684 3000060 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APribosyltrane5bqpA1 A: a/b three-layered sandwichesX: PRTase-like (From Topology)H: PRTase-like (From Topology)T: PRTase-likeF: PribosyltranECOD (1.6)
BPribosyltrane5bqpB1 A: a/b three-layered sandwichesX: PRTase-like (From Topology)H: PRTase-like (From Topology)T: PRTase-likeF: PribosyltranECOD (1.6)
CPribosyltrane5bqpC1 A: a/b three-layered sandwichesX: PRTase-like (From Topology)H: PRTase-like (From Topology)T: PRTase-likeF: PribosyltranECOD (1.6)
DPribosyltrane5bqpD1 A: a/b three-layered sandwichesX: PRTase-like (From Topology)H: PRTase-like (From Topology)T: PRTase-likeF: PribosyltranECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.2020 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
B3.40.50.2020 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
C3.40.50.2020 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)
D3.40.50.2020 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF00156Phosphoribosyl transferase domain (Pribosyltran)Phosphoribosyl transferase domainThis family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7, Swiss:P07672. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase Swiss:P51900. Hypoxanthine phosph ...This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7, Swiss:P07672. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase Swiss:P51900. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8 Swiss:P36766. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1 Swiss:P09329. Amidophosphoribosyltransferase EC:2.4.2.14 Swiss:P00496. Orotate phosphoribosyl-transferase EC:2.4.2.10 Swiss:P11172. Uracil phosphoribosyl-transferase EC:2.4.2.9 Swiss:P25532. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22 Swiss:P00501. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain [1].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
Purine phosphoribosyltransferase (GpT-2) - -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D
IPR000836Phosphoribosyltransferase domainDomain
A, B, C, D
IPR029057Phosphoribosyltransferase-likeHomologous Superfamily