Annotations: 5GSM

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	EUF07802	e5gsmA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Beta-galactosidase LacA beta-sandwich domain (From Topology)	T: Beta-galactosidase LacA beta-sandwich domain	F: EUF07802	ECOD (1.6)
A	EUF07813	e5gsmA3	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycosyl hydrolase domain (From Topology)	T: Glycosyl hydrolase domain	F: EUF07813	ECOD (1.6)
A	Glyco_hydro_42	e5gsmA4	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_42	ECOD (1.6)
A	Glyco_hydro_42M	e5gsmA2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Class I glutamine amidotransferase-like	F: Glyco_hydro_42M	ECOD (1.6)
B	EUF07802	e5gsmB4	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Beta-galactosidase LacA beta-sandwich domain (From Topology)	T: Beta-galactosidase LacA beta-sandwich domain	F: EUF07802	ECOD (1.6)
B	EUF07813	e5gsmB1	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: Glycosyl hydrolase domain (From Topology)	T: Glycosyl hydrolase domain	F: EUF07813	ECOD (1.6)
B	Glyco_hydro_42	e5gsmB2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_42	ECOD (1.6)
B	Glyco_hydro_42M	e5gsmB3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Class I glutamine amidotransferase-like	F: Glyco_hydro_42M	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02449	Beta-galactosidase (Glyco_hydro_42)	Beta-galactosidase	This group of beta-galactosidase enzymes belong to the glycosyl hydrolase 42 family. The enzyme catalyses the hydrolysis of terminal, non-reducing terminal beta-D-galactosidase residues.	Domain
A, B	PF22345	GLMA, C-terminal (GLMA_C)	GLMA-like, C-terminal	This entry represents a beta-sandwich domain found at the C-terminal of exo-beta-D-glucosaminidase GLMA from Thermococcus kodakarensis and similar archaeal proteins. It is an exo-type enzyme that specifically cleaves the non-reducing terminal glycosi ...	This entry represents a beta-sandwich domain found at the C-terminal of exo-beta-D-glucosaminidase GLMA from Thermococcus kodakarensis and similar archaeal proteins. It is an exo-type enzyme that specifically cleaves the non-reducing terminal glycosidic bond of chitooligosaccharides, being involved in chitin degradation [1-3].	Domain
A, B	PF22369	GLMA-like, second domain (GLMA_2nd)	GLMA-like, glycosyl hydrolase domain	This entry represents an all-beta domain (GHD) found towards the C-terminal of exo-beta-D-glucosaminidase GLMA from Thermococcus kodakarensis and similar archaeal proteins, just before the C-terminal domain (Pfam:PF22345). It is an exo-type enzyme th ...	This entry represents an all-beta domain (GHD) found towards the C-terminal of exo-beta-D-glucosaminidase GLMA from Thermococcus kodakarensis and similar archaeal proteins, just before the C-terminal domain (Pfam:PF22345). It is an exo-type enzyme that specifically cleaves the non-reducing terminal glycosidic bond of chitooligosaccharides, being involved in chitin degradation [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Exo-beta-D-glucosaminidase	hydrolase activity, acting on glycosyl bonds beta-galactosidase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity galactosidase activity 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose exo-beta-D-glucosaminidase activity	carbohydrate derivative catabolic process catabolic process carbohydrate derivative metabolic process chitin metabolic process aminoglycan catabolic process macromolecule catabolic process glucosamine-containing compound catabolic process amino sugar catabolic process aminoglycan metabolic process amino sugar metabolic process metabolic process cellular process macromolecule metabolic process chitin catabolic process carbohydrate derivative catabolic process catabolic process carbohydrate derivative metabolic process chitin metabolic process aminoglycan catabolic process macromolecule catabolic process glucosamine-containing compound catabolic process amino sugar catabolic process aminoglycan metabolic process amino sugar metabolic process metabolic process cellular process macromolecule metabolic process chitin catabolic process glucosamine-containing compound metabolic process carbohydrate metabolic process primary metabolic process	protein-containing complex catalytic complex beta-galactosidase complex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure organelle vacuole cytoplasm intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR029062	Class I glutamine amidotransferase-like	Homologous Superfamily
A, B	IPR001944	Glycoside hydrolase, family 35	Family
A, B	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A, B	IPR053516	Exo-beta-D-glucosaminidase	Family
A, B	IPR013529	Glycoside hydrolase, family 42, N-terminal	Domain
A, B	IPR054747	GLMA-like, C-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.