Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad4nqca2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad4nqca1 Alpha and beta proteins (a+b) MHC antigen-recognition domain MHC antigen-recognition domain automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad4nqca3 Artifacts Tags Tags Tags N-terminal Tags human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd4nqcc2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd4nqcc1 Alpha and beta proteins (a+b) MHC antigen-recognition domain MHC antigen-recognition domain automated matches automated matches human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd4nqcc3 Artifacts Tags Tags Tags N-terminal Tags human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Fd4nqcf_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) beta2-microglobulin human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd4nqcb_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) beta2-microglobulin human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Dd4nqcd2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Dd4nqcd1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Gd4nqcg2 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin C1 set domains (antibody constant domain-like) automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Gd4nqcg1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Hd4nqch1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ed4nqce1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
FSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8003766 3000071 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8003766 3000071 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8054555 3000071 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8054555 3000071 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AC1-set_2e4nqcA2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
AMHC_Ie4nqcA1 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_IECOD (1.6)
CC1-set_2e4nqcC2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
CMHC_Ie4nqcC1 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_IECOD (1.6)
FC1-set_2e4nqcF1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
BC1-set_2e4nqcB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
DDUF1968e4nqcD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF1968ECOD (1.6)
DV-set_3e4nqcD2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
GDUF1968e4nqcG1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF1968ECOD (1.6)
GV-set_3e4nqcG2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
HC1-sete4nqcH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-setECOD (1.6)
HV-set_3e4nqcH2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
EC1-sete4nqcE1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-setECOD (1.6)
EV-set_3e4nqcE2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
A, C
MR1 I-ALPHA-LIKE Homo sapiens (human) MR1*01 G-DOMAIN G-ALPHA1-LIKE, G-DOMAIN G-ALPHA2-LIKE, C-LIKE-DOMAIN C-LIKE RPI-MH1Like MH1LIKE-ALPHA-LIKE_B2M IMGT (202448-0)
B, F
MR1 B2M Homo sapiens (human) B2M*01, B2M*02 C-LIKE-DOMAIN C-LIKE RPI-MH1Like MH1LIKE-ALPHA-LIKE_B2M IMGT (202448-0)
D, G
TR MAIT TRAV1-2*04-TRAJ33*01, TRBV6-1*01 TR-ALPHA Homo sapiens (human) TRAV1-2*01, TRAJ33*01, TRAC*01 V-DOMAIN V-ALPHA, C-DOMAIN C-ALPHA TR TR-ALPHA_BETA-2 IMGT (202448-0)
E, H
TR MAIT TRAV1-2*04-TRAJ33*01, TRBV6-1*01 TR-BETA-2 Homo sapiens (human) TRBV6-1*01, TRBJ2-2*01, TRBC2*01, TRBC2*02 V-DOMAIN V-BETA, C-DOMAIN C-BETA-2 TR TR-ALPHA_BETA-2 IMGT (202448-0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C
PF00129Class I Histocompatibility antigen, domains alpha 1 and 2 (MHC_I)Class I Histocompatibility antigen, domains alpha 1 and 2- Domain
A, C
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
B, F
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
D, G
PF07686Immunoglobulin V-set domain (V-set)Immunoglobulin V-set domainThis domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.Domain
D, G
PF09291Domain of unknown function (DUF1968) (DUF1968)Domain of unknown function (DUF1968)Members of this family are found in mammalian T-cell antigen receptor, and adopt an immunoglobulin-like beta-sandwich fold, with seven strands in two beta-sheets in a Greek-key topology. Their exact function has not, as yet, been determined.Domain
E, H
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, C
Major histocompatibility complex class I-related gene protein
B, F
Beta-2-microglobulin
D, G
TCR alpha chain- - -
E, H
TCR beta chain-

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, C
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
A, C
IPR050208Antigen-presenting and immune regulatory MHC class I-relatedFamily
A, C
IPR003597Immunoglobulin C1-setDomain
A, C
IPR011161MHC class I-like antigen recognition-likeDomain
A, C
IPR011162MHC classes I/II-like antigen recognition proteinHomologous Superfamily
A, C
IPR001039MHC class I alpha chain, alpha1 alpha2 domainsDomain
A, C
IPR003006Immunoglobulin/major histocompatibility complex, conserved siteConserved Site
A, C
IPR037055MHC class I-like antigen recognition-like superfamilyHomologous Superfamily
A, C
IPR013783Immunoglobulin-like foldHomologous Superfamily
A, C
IPR007110Immunoglobulin-like domainDomain
B, F
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
B, F
IPR003006Immunoglobulin/major histocompatibility complex, conserved siteConserved Site
B, F
IPR013783Immunoglobulin-like foldHomologous Superfamily
B, F
IPR007110Immunoglobulin-like domainDomain
B, F
IPR050160Major Histocompatibility Complex/ImmunoglobulinFamily
B, F
IPR003597Immunoglobulin C1-setDomain
B, F
IPR015707Beta-2-MicroglobulinFamily
D, G
IPR052051T cell receptor complex componentFamily
D, G
IPR013783Immunoglobulin-like foldHomologous Superfamily
D, G
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
D, G
IPR013106Immunoglobulin V-set domainDomain
D, G
IPR003599Immunoglobulin domain subtypeDomain
D, G
IPR007110Immunoglobulin-like domainDomain
D, G
IPR015370T-cell receptor alpha chain, constant domainDomain
E, H
IPR003597Immunoglobulin C1-setDomain
E, H
IPR013783Immunoglobulin-like foldHomologous Superfamily
E, H
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
E, H
IPR007110Immunoglobulin-like domainDomain
E, H
IPR050380Immune Recognition and Response ModulatorsFamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, C
PharosQ95460
B, F
PharosP61769