3AKM
X-ray structure of iFABP from human and rat with bound fluorescent fatty acid analogue
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d3akmb_ | All beta proteins | Lipocalins | Lipocalins | Fatty acid binding protein-like | Intestinal fatty acid binding protein | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
C | d3akmc_ | All beta proteins | Lipocalins | Lipocalins | Fatty acid binding protein-like | Intestinal fatty acid binding protein | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
A | d3akma_ | All beta proteins | Lipocalins | Lipocalins | Fatty acid binding protein-like | Intestinal fatty acid binding protein | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
D | d3akmd_ | All beta proteins | Lipocalins | Lipocalins | Fatty acid binding protein-like | Intestinal fatty acid binding protein | human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | Lipocalins | 8032433 | 3001332 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Lipocalins | 8032433 | 3001332 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Lipocalins | 8032433 | 3001332 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Lipocalins | 8032433 | 3001332 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | Lipocalin_7 | e3akmB1 | A: beta barrels | X: Lipocalins/Streptavidin | H: Lipocalins (From Topology) | T: Lipocalins | F: Lipocalin_7 | ECOD (1.6) |
C | Lipocalin_7 | e3akmC1 | A: beta barrels | X: Lipocalins/Streptavidin | H: Lipocalins (From Topology) | T: Lipocalins | F: Lipocalin_7 | ECOD (1.6) |
A | Lipocalin_7 | e3akmA1 | A: beta barrels | X: Lipocalins/Streptavidin | H: Lipocalins (From Topology) | T: Lipocalins | F: Lipocalin_7 | ECOD (1.6) |
D | Lipocalin_7 | e3akmD1 | A: beta barrels | X: Lipocalins/Streptavidin | H: Lipocalins (From Topology) | T: Lipocalins | F: Lipocalin_7 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 2.40.128.20 | Mainly Beta | Beta Barrel | Lipocalin | Calycin beta-barrel core domain | CATH (4.3.0) |
C | 2.40.128.20 | Mainly Beta | Beta Barrel | Lipocalin | Calycin beta-barrel core domain | CATH (4.3.0) |
A | 2.40.128.20 | Mainly Beta | Beta Barrel | Lipocalin | Calycin beta-barrel core domain | CATH (4.3.0) |
D | 2.40.128.20 | Mainly Beta | Beta Barrel | Lipocalin | Calycin beta-barrel core domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00061 | Lipocalin / cytosolic fatty-acid binding protein family (Lipocalin) | Lipocalin / cytosolic fatty-acid binding protein family | Lipocalins are transporters for small hydrophobic molecules, such as lipids, steroid hormones, bilins, and retinoids. The family also encompasses the enzyme prostaglandin D synthase (EC:5.3.99.2). Alignment subsumes both the lipocalin and fatty acid ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR000463 | Cytosolic fatty-acid binding | Domain | |
IPR012674 | Calycin | Homologous Superfamily | |
IPR031272 | Fatty acid-binding protein, intestinal | Family | |
IPR031259 | Intracellular lipid binding protein | Family | |
IPR000566 | Lipocalin/cytosolic fatty-acid binding domain | Domain |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
P12104 | :