2GSG

Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2gsga_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Cd2gsgc_ All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin automated matches automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Bd2gsgb1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin V set domains (antibody variable domain-like) automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Bd2gsgb2 Artifacts Tags Tags Tags N-terminal Tags house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Dd2gsgd1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin V set domains (antibody variable domain-like) automated matches house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)
Dd2gsgd2 Artifacts Tags Tags Tags N-terminal Tags house mouse (Mus musculus ) [TaxId: 10090 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AV-set_3e2gsgA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
CV-set_3e2gsgC1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
BV-set_8e2gsgB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
DV-set_8e2gsgD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
C2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
B2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
D2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
A, C
MW1, anti-poly-glutamine (polyQ) V-LAMBDA Mus musculus (house mouse) IGLV3*01, IGLJ2*01 V-DOMAIN V-LAMBDA IG FV-HEAVY_LAMBDA IMGT (202451-0)
B, D
MW1, anti-poly-glutamine (polyQ) VH Mus musculus (house mouse) IGHV5-12*01, IGHJ3*01 V-DOMAIN VH IG FV-HEAVY_LAMBDA IMGT (202451-0)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
A, C
Light ChainIGLV3 Lambda-SAbDab (2024-12-27)
B, D
Heavy ChainIGHV5 --SAbDab (2024-12-27)