2AHC

Chorismate lyase with inhibitor Vanilate

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2ahca_	Alpha and beta proteins (a+b)	Chorismate lyase-like	Chorismate lyase-like	Chorismate lyase	Chorismate lyase	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
C	d2ahcc_	Alpha and beta proteins (a+b)	Chorismate lyase-like	Chorismate lyase-like	Chorismate lyase	Chorismate lyase	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
D	d2ahcd_	Alpha and beta proteins (a+b)	Chorismate lyase-like	Chorismate lyase-like	Chorismate lyase	Chorismate lyase	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d2ahcb_	Alpha and beta proteins (a+b)	Chorismate lyase-like	Chorismate lyase-like	Chorismate lyase	Chorismate lyase	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Chorismate lyase-like	8032520	3000072	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Chorismate lyase-like	8032520	3000072	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Chorismate lyase-like	8032520	3000072	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Chorismate lyase-like	8032520	3000072	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Chor_lyase	e2ahcA1	A: a+b two layers	X: Chorismate lyase (From Topology)	H: Chorismate lyase (From Topology)	T: Chorismate lyase	F: Chor_lyase	ECOD (1.6)
C	Chor_lyase	e2ahcC1	A: a+b two layers	X: Chorismate lyase (From Topology)	H: Chorismate lyase (From Topology)	T: Chorismate lyase	F: Chor_lyase	ECOD (1.6)
D	Chor_lyase	e2ahcD1	A: a+b two layers	X: Chorismate lyase (From Topology)	H: Chorismate lyase (From Topology)	T: Chorismate lyase	F: Chor_lyase	ECOD (1.6)
B	Chor_lyase	e2ahcB1	A: a+b two layers	X: Chorismate lyase (From Topology)	H: Chorismate lyase (From Topology)	T: Chorismate lyase	F: Chor_lyase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.1410.10	Alpha Beta	3-Layer(aba) Sandwich	Chorismate lyase	Chorismate lyase-like	CATH (4.3.0)
C	3.40.1410.10	Alpha Beta	3-Layer(aba) Sandwich	Chorismate lyase	Chorismate lyase-like	CATH (4.3.0)
D	3.40.1410.10	Alpha Beta	3-Layer(aba) Sandwich	Chorismate lyase	Chorismate lyase-like	CATH (4.3.0)
B	3.40.1410.10	Alpha Beta	3-Layer(aba) Sandwich	Chorismate lyase	Chorismate lyase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF04345	Chorismate lyase (Chor_lyase)	Chorismate lyase	Chorismate lyase catalyses the first step in ubiquinone synthesis, i.e. the removal of pyruvate from chorismate, to yield 4-hydroxybenzoate.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Chorismate lyase	chorismate lyase activity oxo-acid-lyase activity lyase activity catalytic activity carbon-carbon lyase activity	pyruvate metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process biosynthetic process pyruvate biosynthetic process small molecule metabolic process metabolic process cellular process monocarboxylic acid metabolic process pyruvate metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process biosynthetic process pyruvate biosynthetic process small molecule metabolic process metabolic process cellular process monocarboxylic acid metabolic process ketone metabolic process ubiquinone biosynthetic process quinone metabolic process quinone biosynthetic process ubiquinone metabolic process ketone biosynthetic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR028978	Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily	Homologous Superfamily
A, B, C, D	IPR007440	Chorismate--pyruvate lyase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.