Annotations: 1O7X

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1o7xa_	All alpha proteins	Citrate synthase	Citrate synthase	Citrate synthase	Citrate synthase	(Saccharolobus solfataricus ) [TaxId: 2287 ],	SCOPe (2.08)
B	d1o7xb_	All alpha proteins	Citrate synthase	Citrate synthase	Citrate synthase	Citrate synthase	(Saccharolobus solfataricus ) [TaxId: 2287 ],	SCOPe (2.08)
D	d1o7xd_	All alpha proteins	Citrate synthase	Citrate synthase	Citrate synthase	Citrate synthase	(Saccharolobus solfataricus ) [TaxId: 2287 ],	SCOPe (2.08)
C	d1o7xc_	All alpha proteins	Citrate synthase	Citrate synthase	Citrate synthase	Citrate synthase	(Saccharolobus solfataricus ) [TaxId: 2287 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Citrate synthase	8031713	4001201	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Citrate synthase	8044091	3001050	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Citrate synthase	8044091	3001050	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Citrate synthase	8044091	3001050	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Citrate synthase	8044091	3001050	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Citrate_synt	e1o7xA1	A: alpha complex topology	X: Citrate synthase-like	H: Citrate synthase (From Topology)	T: Citrate synthase	F: Citrate_synt	ECOD (1.6)
B	Citrate_synt	e1o7xB1	A: alpha complex topology	X: Citrate synthase-like	H: Citrate synthase (From Topology)	T: Citrate synthase	F: Citrate_synt	ECOD (1.6)
D	Citrate_synt	e1o7xD1	A: alpha complex topology	X: Citrate synthase-like	H: Citrate synthase (From Topology)	T: Citrate synthase	F: Citrate_synt	ECOD (1.6)
C	Citrate_synt	e1o7xC1	A: alpha complex topology	X: Citrate synthase-like	H: Citrate synthase (From Topology)	T: Citrate synthase	F: Citrate_synt	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.580.10	Mainly Alpha	Orthogonal Bundle	Citrate Synthase	domain 1	CATH (4.3.0)
A	1.10.230.10	Mainly Alpha	Orthogonal Bundle	Cytochrome p450-Terp	domain 2	CATH (4.3.0)
B	1.10.580.10	Mainly Alpha	Orthogonal Bundle	Citrate Synthase	domain 1	CATH (4.3.0)
B	1.10.230.10	Mainly Alpha	Orthogonal Bundle	Cytochrome p450-Terp	domain 2	CATH (4.3.0)
D	1.10.580.10	Mainly Alpha	Orthogonal Bundle	Citrate Synthase	domain 1	CATH (4.3.0)
D	1.10.230.10	Mainly Alpha	Orthogonal Bundle	Cytochrome p450-Terp	domain 2	CATH (4.3.0)
C	1.10.580.10	Mainly Alpha	Orthogonal Bundle	Citrate Synthase	domain 1	CATH (4.3.0)
C	1.10.230.10	Mainly Alpha	Orthogonal Bundle	Cytochrome p450-Terp	domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00285	Citrate synthase, C-terminal domain (Citrate_synt)	Citrate synthase, C-terminal domain	This is the long, C-terminal part of the enzyme.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	CITRATE SYNTHASE	citrate (Si)-synthase activity citrate synthase activity acyltransferase activity acyltransferase activity, acyl groups converted into alkyl on transfer transferase activity catalytic activity	aerobic respiration cellular respiration tricarboxylic acid cycle energy derivation by oxidation of organic compounds metabolic process cellular process primary metabolic process generation of precursor metabolites and energy carbohydrate metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR054926	Citrate synthase family	Family
A, B, C, D	IPR024176	Citrate synthase, bacterial-type	Family
A, B, C, D	IPR036969	Citrate synthase superfamily	Homologous Superfamily
A, B, C, D	IPR011278	2-methylcitrate synthase/citrate synthase type I	Family
A, B, C, D	IPR019810	Citrate synthase active site	Active Site
A, B, C, D	IPR016143	Citrate synthase-like, small alpha subdomain	Homologous Superfamily
A, B, C, D	IPR002020	Citrate synthase	Family
A, B, C, D	IPR016142	Citrate synthase-like, large alpha subdomain	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.