1K32

Crystal structure of the tricorn protease

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Structure Motif: Primary M-CSA Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
E	d1k32e1	All beta proteins	PDZ domain-like	PDZ domain-like	Tail specific protease PDZ domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
E	d1k32e2	All beta proteins	6-bladed beta-propeller	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
E	d1k32e3	All beta proteins	7-bladed beta-propeller	Tricorn protease domain 2	Tricorn protease domain 2	Tricorn protease domain 2	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
E	d1k32e4	Alpha and beta proteins (a/b)	ClpP/crotonase	ClpP/crotonase	Tail specific protease, catalytic domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
F	d1k32f1	All beta proteins	PDZ domain-like	PDZ domain-like	Tail specific protease PDZ domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
F	d1k32f2	All beta proteins	6-bladed beta-propeller	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
F	d1k32f3	All beta proteins	7-bladed beta-propeller	Tricorn protease domain 2	Tricorn protease domain 2	Tricorn protease domain 2	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
F	d1k32f4	Alpha and beta proteins (a/b)	ClpP/crotonase	ClpP/crotonase	Tail specific protease, catalytic domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
A	d1k32a1	All beta proteins	PDZ domain-like	PDZ domain-like	Tail specific protease PDZ domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
A	d1k32a2	All beta proteins	6-bladed beta-propeller	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
A	d1k32a3	All beta proteins	7-bladed beta-propeller	Tricorn protease domain 2	Tricorn protease domain 2	Tricorn protease domain 2	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
A	d1k32a4	Alpha and beta proteins (a/b)	ClpP/crotonase	ClpP/crotonase	Tail specific protease, catalytic domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
B	d1k32b1	All beta proteins	PDZ domain-like	PDZ domain-like	Tail specific protease PDZ domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
B	d1k32b2	All beta proteins	6-bladed beta-propeller	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
B	d1k32b3	All beta proteins	7-bladed beta-propeller	Tricorn protease domain 2	Tricorn protease domain 2	Tricorn protease domain 2	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
B	d1k32b4	Alpha and beta proteins (a/b)	ClpP/crotonase	ClpP/crotonase	Tail specific protease, catalytic domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
C	d1k32c1	All beta proteins	PDZ domain-like	PDZ domain-like	Tail specific protease PDZ domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
C	d1k32c2	All beta proteins	6-bladed beta-propeller	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
C	d1k32c3	All beta proteins	7-bladed beta-propeller	Tricorn protease domain 2	Tricorn protease domain 2	Tricorn protease domain 2	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
C	d1k32c4	Alpha and beta proteins (a/b)	ClpP/crotonase	ClpP/crotonase	Tail specific protease, catalytic domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
D	d1k32d1	All beta proteins	PDZ domain-like	PDZ domain-like	Tail specific protease PDZ domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
D	d1k32d2	All beta proteins	6-bladed beta-propeller	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
D	d1k32d3	All beta proteins	7-bladed beta-propeller	Tricorn protease domain 2	Tricorn protease domain 2	Tricorn protease domain 2	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)
D	d1k32d4	Alpha and beta proteins (a/b)	ClpP/crotonase	ClpP/crotonase	Tail specific protease, catalytic domain	Tricorn protease	(Thermoplasma acidophilum ) [TaxId: 2303 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
E	SCOP2B Superfamily	Tricorn protease N-terminal domain	8037767	3000291	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Tricorn protease domain 2	8037768	3000315	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	PDZ domain-like	8037766	3000388	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Tricorn protease domain 2	8037768	3000315	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Tricorn protease N-terminal domain	8037767	3000291	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	PDZ domain-like	8037766	3000388	SCOP2B (2022-06-29)
A	SCOP2 Family	Tail specific protease PDZ domain	8025387	4002827	SCOP2 (2022-06-29)
A	SCOP2 Family	Tricorn protease N-terminal domain	8025388	4003126	SCOP2 (2022-06-29)
A	SCOP2 Family	Tricorn protease domain 2	8025389	4003140	SCOP2 (2022-06-29)
A	SCOP2 Family	Tail specific protease, catalytic domain	8025390	4003564	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PDZ domain-like	8037766	3000388	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Tricorn protease N-terminal domain	8037767	3000291	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Tricorn protease domain 2	8037768	3000315	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	ClpP/crotonase	8037769	3000033	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	PDZ domain-like	8037766	3000388	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Tricorn protease domain 2	8037768	3000315	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Tricorn protease N-terminal domain	8037767	3000291	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Tricorn protease domain 2	8037768	3000315	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Tricorn protease N-terminal domain	8037767	3000291	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	PDZ domain-like	8037766	3000388	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Tricorn protease N-terminal domain	8037767	3000291	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	PDZ domain-like	8037766	3000388	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Tricorn protease domain 2	8037768	3000315	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	ClpP/crotonase	8037769	3000033	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
E	Tricorn_PDZ	e1k32E3	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: Tricorn_PDZ	ECOD (1.6)
E	DPPIV_N_1	e1k32E1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: DPPIV_N_1	ECOD (1.6)
E	DPPIV_N	e1k32E5	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: DPPIV_N	ECOD (1.6)
E	Tricorn_C1	e1k32E2	A: alpha bundles	X: Tail specific protease helical domain (From Topology)	H: Tail specific protease helical domain (From Topology)	T: Tail specific protease helical domain	F: Tricorn_C1	ECOD (1.6)
E	Peptidase_S41	e1k32E4	A: a/b three-layered sandwiches	X: ClpP/crotonase (From Topology)	H: ClpP/crotonase (From Topology)	T: ClpP/crotonase	F: Peptidase_S41	ECOD (1.6)
F	Tricorn_PDZ	e1k32F2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: Tricorn_PDZ	ECOD (1.6)
F	DPPIV_N_1	e1k32F1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: DPPIV_N_1	ECOD (1.6)
F	DPPIV_N	e1k32F5	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: DPPIV_N	ECOD (1.6)
F	Tricorn_C1	e1k32F3	A: alpha bundles	X: Tail specific protease helical domain (From Topology)	H: Tail specific protease helical domain (From Topology)	T: Tail specific protease helical domain	F: Tricorn_C1	ECOD (1.6)
F	Peptidase_S41	e1k32F4	A: a/b three-layered sandwiches	X: ClpP/crotonase (From Topology)	H: ClpP/crotonase (From Topology)	T: ClpP/crotonase	F: Peptidase_S41	ECOD (1.6)
A	Tricorn_PDZ	e1k32A1	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: Tricorn_PDZ	ECOD (1.6)
A	DPPIV_N_1	e1k32A2	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: DPPIV_N_1	ECOD (1.6)
A	DPPIV_N	e1k32A3	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: DPPIV_N	ECOD (1.6)
A	Tricorn_C1	e1k32A5	A: alpha bundles	X: Tail specific protease helical domain (From Topology)	H: Tail specific protease helical domain (From Topology)	T: Tail specific protease helical domain	F: Tricorn_C1	ECOD (1.6)
A	Peptidase_S41	e1k32A6	A: a/b three-layered sandwiches	X: ClpP/crotonase (From Topology)	H: ClpP/crotonase (From Topology)	T: ClpP/crotonase	F: Peptidase_S41	ECOD (1.6)
B	Tricorn_PDZ	e1k32B4	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: Tricorn_PDZ	ECOD (1.6)
B	DPPIV_N_1	e1k32B2	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: DPPIV_N_1	ECOD (1.6)
B	DPPIV_N	e1k32B5	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: DPPIV_N	ECOD (1.6)
B	Tricorn_C1	e1k32B3	A: alpha bundles	X: Tail specific protease helical domain (From Topology)	H: Tail specific protease helical domain (From Topology)	T: Tail specific protease helical domain	F: Tricorn_C1	ECOD (1.6)
B	Peptidase_S41	e1k32B1	A: a/b three-layered sandwiches	X: ClpP/crotonase (From Topology)	H: ClpP/crotonase (From Topology)	T: ClpP/crotonase	F: Peptidase_S41	ECOD (1.6)
C	Tricorn_PDZ	e1k32C4	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: Tricorn_PDZ	ECOD (1.6)
C	DPPIV_N_1	e1k32C2	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: DPPIV_N_1	ECOD (1.6)
C	DPPIV_N	e1k32C5	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: DPPIV_N	ECOD (1.6)
C	Tricorn_C1	e1k32C3	A: alpha bundles	X: Tail specific protease helical domain (From Topology)	H: Tail specific protease helical domain (From Topology)	T: Tail specific protease helical domain	F: Tricorn_C1	ECOD (1.6)
C	Peptidase_S41	e1k32C1	A: a/b three-layered sandwiches	X: ClpP/crotonase (From Topology)	H: ClpP/crotonase (From Topology)	T: ClpP/crotonase	F: Peptidase_S41	ECOD (1.6)
D	Tricorn_PDZ	e1k32D2	A: beta barrels	X: PDZ domain (From Topology)	H: PDZ domain (From Topology)	T: PDZ domain	F: Tricorn_PDZ	ECOD (1.6)
D	DPPIV_N_1	e1k32D5	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 6-bladed	F: DPPIV_N_1	ECOD (1.6)
D	DPPIV_N	e1k32D1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: DPPIV_N	ECOD (1.6)
D	Tricorn_C1	e1k32D4	A: alpha bundles	X: Tail specific protease helical domain (From Topology)	H: Tail specific protease helical domain (From Topology)	T: Tail specific protease helical domain	F: Tricorn_C1	ECOD (1.6)
D	Peptidase_S41	e1k32D3	A: a/b three-layered sandwiches	X: ClpP/crotonase (From Topology)	H: ClpP/crotonase (From Topology)	T: ClpP/crotonase	F: Peptidase_S41	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
E	2.120.10.60	Mainly Beta	6 Propeller	Neuraminidase	Tricorn protease N-terminal domain	CATH (4.3.0)
E	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
E	3.30.750.44	Alpha Beta	2-Layer Sandwich	Transcription Regulator spoIIAA		CATH (4.3.0)
E	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
E	3.90.226.10	Alpha Beta	Alpha-Beta Complex	2-enoyl-CoA Hydratase	Chain A, domain 1	CATH (4.3.0)
F	2.120.10.60	Mainly Beta	6 Propeller	Neuraminidase	Tricorn protease N-terminal domain	CATH (4.3.0)
F	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
F	3.30.750.44	Alpha Beta	2-Layer Sandwich	Transcription Regulator spoIIAA		CATH (4.3.0)
F	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
F	3.90.226.10	Alpha Beta	Alpha-Beta Complex	2-enoyl-CoA Hydratase	Chain A, domain 1	CATH (4.3.0)
A	2.120.10.60	Mainly Beta	6 Propeller	Neuraminidase	Tricorn protease N-terminal domain	CATH (4.3.0)
A	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
A	3.30.750.44	Alpha Beta	2-Layer Sandwich	Transcription Regulator spoIIAA		CATH (4.3.0)
A	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
A	3.90.226.10	Alpha Beta	Alpha-Beta Complex	2-enoyl-CoA Hydratase	Chain A, domain 1	CATH (4.3.0)
B	2.120.10.60	Mainly Beta	6 Propeller	Neuraminidase	Tricorn protease N-terminal domain	CATH (4.3.0)
B	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
B	3.30.750.44	Alpha Beta	2-Layer Sandwich	Transcription Regulator spoIIAA		CATH (4.3.0)
B	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
B	3.90.226.10	Alpha Beta	Alpha-Beta Complex	2-enoyl-CoA Hydratase	Chain A, domain 1	CATH (4.3.0)
C	2.120.10.60	Mainly Beta	6 Propeller	Neuraminidase	Tricorn protease N-terminal domain	CATH (4.3.0)
C	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
C	3.30.750.44	Alpha Beta	2-Layer Sandwich	Transcription Regulator spoIIAA		CATH (4.3.0)
C	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
C	3.90.226.10	Alpha Beta	Alpha-Beta Complex	2-enoyl-CoA Hydratase	Chain A, domain 1	CATH (4.3.0)
D	2.120.10.60	Mainly Beta	6 Propeller	Neuraminidase	Tricorn protease N-terminal domain	CATH (4.3.0)
D	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
D	3.30.750.44	Alpha Beta	2-Layer Sandwich	Transcription Regulator spoIIAA		CATH (4.3.0)
D	2.30.42.10	Mainly Beta	Roll	Pdz3 Domain	PDZ domain	CATH (4.3.0)
D	3.90.226.10	Alpha Beta	Alpha-Beta Complex	2-enoyl-CoA Hydratase	Chain A, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF03572	Peptidase family S41 (Peptidase_S41)	Peptidase family S41	-	Family
A, B, C, D, E A, B, C, D, E, F	PF14684	Tricorn protease C1 domain (Tricorn_C1)	Tricorn protease C1 domain	This domain is the C1 core domain of tricorn protease. This is a mixed alpha-beta domain [1].	Domain
A, B, C, D, E A, B, C, D, E, F	PF14685	Tricorn protease PDZ domain (Tricorn_PDZ)	Tricorn protease PDZ domain	This domain is the PDZ domain of tricorn protease [1].	Domain
A, B, C, D, E A, B, C, D, E, F	PF07676	WD40-like Beta Propeller Repeat (PD40)	WD40-like Beta Propeller Repeat	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	tricorn protease	peptidase activity serine hydrolase activity catalytic activity, acting on a protein serine-type peptidase activity hydrolase activity catalytic activity	proteolysis metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR005151	Tail specific protease	Domain
A, B, C, D, E A, B, C, D, E, F	IPR029045	ClpP/crotonase-like domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR011659	WD40-like beta propeller	Repeat
A, B, C, D, E A, B, C, D, E, F	IPR028204	Tricorn protease C1 domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR029414	Tricorn protease, PDZ domain	Domain
A, B, C, D, E A, B, C, D, E, F	IPR012393	Tricorn protease	Family
A, B, C, D, E A, B, C, D, E, F	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR036034	PDZ superfamily	Homologous Superfamily

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A	tricorn protease M-CSA #808	The tricorn protease is the core of a proteolytic system identified in the model organism Thermoplasma acidophilum. This complex functions to degrade the 7-9 residue peptides that are produced by the proteasome-mediated degradation of cellular proteins. The basic functional unit of the tricorn protease is a homohexamer of the 121 kDa subunit; however electron microscopy studies indicate that 20 copies of this 720 kDa hexamer can assemble further in vivo to form a giant 14.6 MDa icosahedral capsid.	Defined by 4 residues: HIS:A-720 [auth A-746]GLY:A-892 [auth A-918]SER:A-939 [auth A-965]ASP:A-940 [auth A-966] \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 3.4.21 (PDB Primary Data) Search M-CSA Motif + EC 3.4.21