8H7X | pdb_00008h7x

Crystal structure of EGFR T790M/C797S mutant in complex with brigatinib

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Sequence of
     ​G​​A​​M​​G​​E​​A​​P​​N​​Q​​A​703  ​L​​L​​R​​I​​L​​K​​E​​T​​E​​F​713  ​K​​K​​I​​K​​V​​L​​G​​S​​G​​A​723  ​F​​G​​T​​V​​Y​​K​​G​​L​​W​​I​733  ​P​​E​​G​​E​​K​​V​​K​​I​​P​​V​743  ​A​​I​​K​​E​​L​​R​​E​​A​​T​​S​753  ​P​​K​​A​​N​​K​​E​​I​​L​​D​​E​763  ​A​​Y​​V​​M​​A​​S​​V​​D​​N​​P​773  ​H​​V​​C​​R​​L​​L​​G​​I​​C​​L​783  ​T​​S​​T​​V​​Q​​L​​I​​M​​Q​​L​793  ​M​​P​​F​​G​​S​​L​​L​​D​​Y​​V​803  ​R​​E​​H​​K​​D​​N​​I​​G​​S​​Q​813  ​Y​​L​​L​​N​​W​​C​​V​​Q​​I​​A​823  ​K​​G​​M​​N​​Y​​L​​E​​D​​R​​R​833  ​L​​V​​H​​R​​D​​L​​A​​A​​R​​N​843  ​V​​L​​V​​K​​T​​P​​Q​​H​​V​​K​853  ​I​​T​​D​​F​​G​​L​​A​​K​​L​​L​863  ​G​​A​​E​​E​​K​​E​​Y​​H​​A​​E​873  ​G​​G​​K​​V​​P​​I​​K​​W​​M​​A​883  ​L​​E​​S​​I​​L​​H​​R​​I​​Y​​T​893  ​H​​Q​​S​​D​​V​​W​​S​​Y​​G​​V​903  ​T​​V​​W​​E​​L​​M​​T​​F​​G​​S​913  ​K​​P​​Y​​D​​G​​I​​P​​A​​S​​E​923  ​I​​S​​S​​I​​L​​E​​K​​G​​E​​R​933  ​L​​P​​Q​​P​​P​​I​​C​​T​​I​​D​943  ​V​​Y​​M​​I​​M​​V​​K​​C​​W​​M​953  ​I​​D​​A​​D​​S​​R​​P​​K​​F​​R​963  ​E​​L​​I​​I​​E​​F​​S​​K​​M​​A​973  ​R​​D​​P​​Q​​R​​Y​​L​​V​​I​​Q​983  ​G​​D​​E​​R​​M​​H​​L​​P​​S​​P​     ​T​​D​​S​​N​​F​​Y​​R​​A​​L​​M​     ​D​​E​​E​​D​​M​​D​​D​​V​​V​​D​1013 ​A​​D​​E​​Y​​L​​I​​P​​Q​​Q​​G​
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Asm Id
Dynamic Bonds

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