3D View: 8B8N

Crystal structure of JAK2 JH2-V617F in complex with Cdk2 inhibitor IV

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RCSB PDB Mol* Viewer 2.10.6 [10/28/2024, 3:56:31 PM]
Sequence of
536  ​V​​F​​H​​K​​I​​R​​N​​E​​D​​L​546  ​I​​F​​N​​E​​S​​L​​G​​Q​​G​​T​556  ​F​​T​​K​​I​​F​​K​​G​​V​​R​​R​566  ​E​​V​​G​​D​​Y​​G​​Q​​L​​H​​E​576  ​T​​E​​V​​L​​L​​K​​V​​L​​D​​K​586  ​A​​H​​R​​N​​Y​​S​​E​​S​​F​​F​596  ​E​​A​​A​​S​​M​​M​​S​​K​​L​​S​606  ​H​​K​​H​​L​​V​​L​​N​​Y​​G​​V​616  ​C​​F​​C​​G​​D​​E​​N​​I​​L​​V​626  ​Q​​E​​F​​V​​K​​F​​G​​S​​L​​D​636  ​T​​Y​​L​​K​​K​​N​​K​​N​​C​​I​646  ​N​​I​​L​​W​​K​​L​​E​​V​​A​​K​656  ​Q​​L​​A​​A​​A​​M​​H​​F​​L​​E​666  ​E​​N​​T​​L​​I​​H​​G​​N​​V​​C​676  ​A​​K​​N​​I​​L​​L​​I​​R​​E​​E​686  ​D​​R​​K​​T​​G​​N​​P​​P​​F​​I​696  ​K​​L​​S​​D​​P​​G​​I​​S​​I​​T​706  ​V​​L​​P​​K​​D​​I​​L​​Q​​E​​R​716  ​I​​P​​W​​V​​P​​P​​E​​C​​I​​E​726  ​N​​P​​K​​N​​L​​N​​L​​A​​T​​D​736  ​K​​W​​S​​F​​G​​T​​T​​L​​W​​E​746  ​I​​C​​S​​G​​G​​D​​K​​P​​L​​S​756  ​A​​L​​D​​S​​Q​​R​​K​​L​​Q​​F​766  ​Y​​E​​D​​R​​H​​Q​​L​​P​​A​​P​776  ​K​​A​​A​​E​​L​​A​​N​​L​​I​​N​786  ​N​​C​​M​​D​​Y​​E​​P​​D​​H​​R​796  ​P​​S​​F​​R​​A​​I​​I​​R​​D​​L​806  ​N​​S​​L​​F​​T​​P​​D​​L​​V​​P​     ​R​​G​​S​​H​​H​​H​​H​​H​​H​
Type
Asm Id
Dynamic Bonds

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