7RUN | pdb_00007run

Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrrolo[2,3-d]pyrimidine inhibitor.

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     ​M​​S​​Y​​Y​​H​​H​​H​​H​​H​​H​     ​D​​Y​​D​​I​​P​​T​​T​​E​​N​​L​     ​Y​​F​​Q​​G​​A​​S​​V​​D​​A​​F​710  ​K​​I​​L​​E​​D​​P​​K​​W​​E​​F​720  ​P​​R​​K​​N​​L​​V​​L​​G​​K​​T​730  ​L​​G​​E​​G​​E​​F​​G​​K​​V​​V​740  ​K​​A​​T​​A​​F​​H​​L​​K​​G​​R​750  ​A​​G​​Y​​T​​T​​V​​A​​V​​K​​M​760  ​L​​K​​E​​N​​A​​S​​P​​S​​E​​L​770  ​R​​D​​L​​L​​S​​E​​F​​N​​V​​L​780  ​K​​Q​​V​​N​​H​​P​​H​​V​​I​​K​790  ​L​​Y​​G​​A​​C​​S​​Q​​D​​G​​P​800  ​L​​L​​L​​I​​V​​E​​Y​​A​​K​​PTR​810  ​G​​S​​L​​R​​G​​F​​L​​R​​E​​S​820  ​R​​K​​V​​G​​P​​G​​Y​​L​​G​​S​     ​G​​G​​S​​R​​N​​S​​S​​S​​L​​D​     ​H​​P​​D​​E​​R​​A​​L​​T​​M​​G​850  ​D​​L​​I​​S​​F​​A​​W​​Q​​I​​S​860  ​Q​​G​​M​​Q​​Y​​L​​A​​E​​M​​K​870  ​L​​V​​H​​R​​D​​L​​A​​A​​R​​N​880  ​I​​L​​V​​A​​E​​G​​R​​K​​M​​K​890  ​I​​S​​D​​F​​G​​L​​S​​R​​D​​V​900  ​Y​​E​​E​​D​​S​​PTR​​V​​K​​R​​SEP​910  ​Q​​G​​R​​I​​P​​V​​K​​W​​M​​A​920  ​I​​E​​S​​L​​F​​D​​H​​I​​PTR​​T​930  ​T​​Q​​S​​D​​V​​W​​S​​F​​G​​V​940  ​L​​L​​W​​E​​I​​V​​T​​L​​G​​G​950  ​N​​P​​Y​​P​​G​​I​​P​​P​​E​​R​960  ​L​​F​​N​​L​​L​​K​​T​​G​​H​​R​970  ​M​​E​​R​​P​​D​​N​​C​​S​​E​​E​980  ​M​​Y​​R​​L​​M​​L​​Q​​C​​W​​K​990  ​Q​​E​​P​​D​​K​​R​​P​​V​​F​​A​1000 ​D​​I​​S​​K​​D​​L​​E​​K​​M​​M​1010 ​V​​K​​R​​R​
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Asm Id
Dynamic Bonds

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