3D View: 7KK5

Structure of the catalytic domain of PARP1 in complex with niraparib

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Sequence of
     ​G​​S​​K​​S​​K​​L​​P​​K​​P​​V​670  ​Q​​D​​L​​I​​K​​M​​I​​F​​D​​V​680  ​E​​S​​M​​K​​K​​A​​M​​V​​E​​Y​690  ​E​​I​​D​​L​​Q​​K​​M​​P​​L​​G​700  ​K​​L​​S​​K​​R​​Q​​I​​Q​​A​​A​710  ​Y​​S​​I​​L​​S​​E​​V​​Q​​Q​​A​720  ​V​​S​​Q​​G​​S​​S​​D​​S​​Q​​I​730  ​L​​D​​L​​S​​N​​R​​F​​Y​​T​​L​740  ​I​​P​​H​​D​​F​​G​​M​​K​​K​​P​750  ​P​​L​​L​​N​​N​​A​​D​​S​​V​​Q​760  ​A​​K​​V​​E​​M​​L​​D​​N​​L​​L​770  ​D​​I​​E​​V​​A​​Y​​S​​L​​L​​R​780  ​G​​G​​S​​D​​D​​S​​S​​K​​D​​P​790  ​I​​D​​V​​N​​Y​​E​​K​​L​​K​​T​800  ​D​​I​​K​​V​​V​​D​​R​​D​​S​​E​810  ​E​​A​​E​​I​​I​​R​​K​​Y​​V​​K​820  ​N​​T​​H​​A​​T​​T​​H​​N​​A​​Y​830  ​D​​L​​E​​V​​I​​D​​I​​F​​K​​I​840  ​E​​R​​E​​G​​E​​C​​Q​​R​​Y​​K​850  ​P​​F​​K​​Q​​L​​H​​N​​R​​R​​L​860  ​L​​W​​H​​G​​S​​R​​T​​T​​N​​F​870  ​A​​G​​I​​L​​S​​Q​​G​​L​​R​​I​880  ​A​​P​​P​​E​​A​​P​​V​​T​​G​​Y​890  ​M​​F​​G​​K​​G​​I​​Y​​F​​A​​D​900  ​M​​V​​S​​K​​S​​A​​N​​Y​​C​​H​910  ​T​​S​​Q​​G​​D​​P​​I​​G​​L​​I​920  ​L​​L​​G​​E​​V​​A​​L​​G​​N​​M​930  ​Y​​E​​L​​K​​H​​A​​S​​H​​I​​S​940  ​K​​L​​P​​K​​G​​K​​H​​S​​V​​K​950  ​G​​L​​G​​K​​T​​T​​P​​D​​P​​S​960  ​A​​N​​I​​S​​L​​D​​G​​V​​D​​V​970  ​P​​L​​G​​T​​G​​I​​S​​S​​G​​V​980  ​N​​D​​T​​S​​L​​L​​Y​​N​​E​​Y​990  ​I​​V​​Y​​D​​I​​A​​Q​​V​​N​​L​1000 ​K​​Y​​L​​L​​K​​L​​K​​F​​N​​F​1010 ​K​​T​
Type
Asm Id
Dynamic Bonds

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