3D View: 6Z4B

Crystal Structure of EGFR-T790M/V948R in Complex with Osimertinib and EAI045

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RCSB PDB Mol* Viewer 2.11.1 [12/17/2024, 1:59:56 PM]
Sequence of
     ​G​​S​​H​​M​​A​​S​​G​​E​​A​​P​700  ​N​​Q​​A​​L​​L​​R​​I​​L​​K​​E​710  ​T​​E​​F​​K​​K​​I​​K​​V​​L​​G​720  ​S​​G​​A​​F​​G​​T​​V​​Y​​K​​G​730  ​L​​W​​I​​P​​E​​G​​E​​K​​V​​K​740  ​I​​P​​V​​A​​I​​K​​E​​L​​R​​E​750  ​A​​T​​S​​P​​K​​A​​N​​K​​E​​I​760  ​L​​D​​E​​A​​Y​​V​​M​​A​​S​​V​770  ​D​​N​​P​​H​​V​​C​​R​​L​​L​​G​780  ​I​​C​​L​​T​​S​​T​​V​​Q​​L​​I​790  ​M​​Q​​L​​M​​P​​F​​G​​C​​L​​L​800  ​D​​Y​​V​​R​​E​​H​​K​​D​​N​​I​810  ​G​​S​​Q​​Y​​L​​L​​N​​W​​C​​V​820  ​Q​​I​​A​​K​​G​​M​​N​​Y​​L​​E​830  ​D​​R​​R​​L​​V​​H​​R​​D​​L​​A​840  ​A​​R​​N​​V​​L​​V​​K​​T​​P​​Q​850  ​H​​V​​K​​I​​T​​D​​F​​G​​L​​A​860  ​K​​L​​L​​G​​A​​E​​E​​K​​E​​Y​     ​H​​A​​E​​G​​G​​K​​V​​P​​I​​K​880  ​W​​M​​A​​L​​E​​S​​I​​L​​H​​R​890  ​I​​Y​​T​​H​​Q​​S​​D​​V​​W​​S​900  ​Y​​G​​V​​T​​V​​W​​E​​L​​M​​T​910  ​F​​G​​S​​K​​P​​Y​​D​​G​​I​​P​920  ​A​​S​​E​​I​​S​​S​​I​​L​​E​​K​930  ​G​​E​​R​​L​​P​​Q​​P​​P​​I​​C​940  ​T​​I​​D​​V​​Y​​M​​I​​M​​R​​K​950  ​C​​W​​M​​I​​D​​A​​D​​S​​R​​P​960  ​K​​F​​R​​E​​L​​I​​I​​E​​F​​S​970  ​K​​M​​A​​R​​D​​P​​Q​​R​​Y​​L​980  ​V​​I​​Q​​G​​D​​E​​R​​M​​H​​L​     ​P​​S​​P​​T​​D​​S​​N​​F​​Y​​R​     ​A​​L​​M​​D​​E​​E​​D​​M​​D​​D​     ​V​​V​​D​​A​​D​​E​​Y​​L​​I​​P​     ​Q​​Q​​G​
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Asm Id
Dynamic Bonds

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