6W35 | pdb_00006w35

A new Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry

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RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
54   ​N​​I​​S​​G​​S​​C​​K​​G​​R​​C​64   ​F​​E​​L​​Q​​E​​A​​G​​P​​P​​D​74   ​C​​R​​C​​D​​N​​L​​C​​K​​S​​Y​84   ​T​​S​​C​​C​​H​​D​​F​​D​​E​​L​94   ​C​​L​​K​​T​​A​​R​​G​​W​​E​​C​104  ​T​​K​​D​​R​​C​​G​​E​​V​​R​​N​114  ​E​​E​​N​​A​​C​​H​​C​​S​​E​​D​124  ​C​​L​​A​​R​​G​​D​​C​​C​​T​​N​134  ​Y​​Q​​V​​V​​C​​K​​G​​E​​S​​H​144  ​W​​V​​D​​D​​D​​C​​E​​E​​I​​K​154  ​A​​A​​E​​C​​P​​A​​G​​F​​V​​R​164  ​P​​P​​L​​I​​I​​F​​S​​V​​D​​G​174  ​F​​R​​A​​S​​Y​​M​​K​​K​​G​​S​184  ​K​​V​​M​​P​​N​​I​​E​​K​​L​​R​194  ​S​​C​​G​​T​​H​​S​​P​​Y​​M​​R​204  ​P​​V​​Y​​P​​T​​K​​T​​F​​P​​N​214  ​L​​Y​​T​​L​​A​​T​​G​​L​​Y​​P​224  ​E​​S​​H​​G​​I​​V​​G​​N​​S​​M​234  ​Y​​D​​P​​V​​F​​D​​A​​T​​F​​H​244  ​L​​R​​G​​R​​E​​K​​F​​N​​H​​R​254  ​W​​W​​G​​G​​Q​​P​​L​​W​​I​​T​264  ​A​​T​​K​​Q​​G​​V​​K​​A​​G​​T​274  ​F​​F​​W​​S​​V​​V​​I​​P​​H​​E​284  ​R​​R​​I​​L​​T​​I​​L​​Q​​W​​L​294  ​T​​L​​P​​D​​H​​E​​R​​P​​S​​V​304  ​Y​​A​​F​​Y​​S​​E​​Q​​P​​D​​F​314  ​S​​G​​H​​K​​Y​​G​​P​​F​​G​​P​324  ​E​​M​​T​​N​​P​​L​​R​​E​​I​​D​334  ​K​​I​​V​​G​​Q​​L​​M​​D​​G​​L​344  ​K​​Q​​L​​K​​L​​H​​R​​C​​V​​N​354  ​V​​I​​F​​V​​G​​D​​H​​G​​M​​E​364  ​D​​V​​T​​C​​D​​R​​T​​E​​F​​L​374  ​S​​N​​Y​​L​​T​​N​​V​​D​​D​​I​384  ​T​​L​​V​​P​​G​​T​​L​​G​​R​​I​394  ​R​​S​​K​​F​​S​​N​​N​​A​​K​​Y​404  ​D​​P​​K​​A​​I​​I​​A​​N​​L​​T​414  ​C​​K​​K​​P​​D​​Q​​H​​F​​K​​P​424  ​Y​​L​​K​​Q​​H​​L​​P​​K​​R​​L​434  ​H​​Y​​A​​N​​N​​R​​R​​I​​E​​D​444  ​I​​H​​L​​L​​V​​E​​R​​R​​W​​H​454  ​V​​A​​R​​K​​P​​L​​D​​V​​Y​​K​     ​K​​P​​S​​G​​K​​C​​F​​F​​Q​​G​474  ​D​​H​​G​​F​​D​​N​​K​​V​​N​​S​484  ​M​​Q​​T​​V​​F​​V​​G​​Y​​G​​P​494  ​T​​F​​K​​Y​​K​​T​​K​​V​​P​​P​504  ​F​​E​​N​​I​​E​​L​​Y​​N​​V​​M​514  ​C​​D​​L​​L​​G​​L​​K​​P​​A​​P​524  ​N​​N​​G​​T​​H​​G​​S​​L​​N​​H​534  ​L​​L​​R​​T​​N​​T​​F​​R​​P​​T​544  ​M​​P​​E​​E​​V​​T​​R​​P​​N​​Y​554  ​P​​G​​I​​M​​Y​​L​​Q​​S​​D​​F​564  ​D​​L​​G​​C​​T​​C​​D​​D​​K​​N​574  ​K​​L​​D​​E​​L​​N​​K​​R​​L​​H​584  ​T​​K​​G​​S​​T​​E​​E​​R​​H​​L​594  ​L​​Y​​G​​R​​P​​A​​V​​L​​Y​​R​604  ​T​​R​​Y​​D​​I​​L​​Y​​H​​T​​D​614  ​F​​E​​S​​G​​Y​​S​​E​​I​​F​​L​624  ​M​​P​​L​​W​​T​​S​​Y​​T​​V​​S​634  ​K​​Q​​A​​E​​V​​S​​S​​V​​P​​D​644  ​H​​L​​T​​S​​C​​V​​R​​P​​D​​V​654  ​R​​V​​S​​P​​S​​F​​S​​Q​​N​​C​664  ​L​​A​​Y​​K​​N​​D​​K​​Q​​M​​S​674  ​Y​​G​​F​​L​​F​​P​​P​​Y​​L​​S​684  ​S​​S​​P​​E​​A​​K​​Y​​D​​A​​F​694  ​L​​V​​T​​N​​M​​V​​P​​M​​Y​​P​704  ​A​​F​​K​​R​​V​​W​​N​​Y​​F​​Q​714  ​R​​V​​L​​V​​K​​K​​Y​​A​​S​​E​724  ​R​​N​​G​​V​​N​​V​​I​​S​​G​​P​734  ​I​​F​​D​​Y​​D​​Y​​D​​G​​L​​H​744  ​D​​T​​E​​D​​K​​I​​K​​Q​​Y​​V​754  ​E​​G​​S​​S​​I​​P​​V​​P​​T​​H​764  ​Y​​Y​​S​​I​​I​​T​​S​​C​​L​​D​774  ​F​​T​​Q​​P​​A​​D​​K​​C​​D​​G​784  ​P​​L​​S​​V​​S​​S​​F​​I​​L​​P​794  ​H​​R​​P​​D​​N​​E​​E​​S​​C​​N​804  ​S​​S​​E​​D​​E​​S​​K​​W​​V​​E​814  ​E​​L​​M​​K​​M​​H​​T​​A​​R​​V​824  ​R​​D​​I​​E​​H​​L​​T​​S​​L​​D​834  ​F​​F​​R​​K​​T​​S​​R​​S​​Y​​P​844  ​E​​I​​L​​T​​L​​K​​T​​Y​​L​​H​854  ​T​​Y​​E​​S​​E​​I​​L​​V​​P​​R​     ​G​​S​​H​​H​​H​​H​​H​​H​
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Asm Id
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