6VHG | pdb_00006vhg

Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrazolo[1,5-a]pyrimidine inhibitor

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Sequence of
     ​G​​A​​S​​V​​D​​A​​F​​K​​I​​L​713  ​E​​D​​P​​K​​W​​E​​F​​P​​R​​K​723  ​N​​L​​V​​L​​G​​K​​T​​L​​G​​E​733  ​G​​E​​F​​G​​K​​V​​V​​K​​A​​T​743  ​A​​F​​H​​L​​K​​G​​R​​A​​G​​Y​753  ​T​​T​​V​​A​​V​​K​​M​​L​​K​​E​763  ​N​​A​​S​​P​​S​​E​​L​​R​​D​​L​773  ​L​​S​​E​​F​​N​​V​​L​​K​​Q​​V​783  ​N​​H​​P​​H​​V​​I​​K​​L​​Y​​G​793  ​A​​C​​S​​Q​​D​​G​​P​​L​​L​​L​803  ​I​​V​​E​​Y​​A​​K​​Y​​G​​S​​L​813  ​R​​G​​F​​L​​R​​E​​S​​R​​K​​V​     ​G​​P​​G​​Y​​L​​G​​S​​G​​G​​S​     ​R​​N​​S​​S​​S​​L​​D​​H​​P​​D​     ​E​​R​​A​​L​​T​​M​​G​​D​​L​​I​853  ​S​​F​​A​​W​​Q​​I​​S​​Q​​G​​M​863  ​Q​​Y​​L​​A​​E​​M​​K​​L​​V​​H​873  ​R​​D​​L​​A​​A​​R​​N​​I​​L​​V​883  ​A​​E​​G​​R​​K​​M​​K​​I​​S​​D​893  ​F​​G​​L​​S​​R​​D​​V​​Y​​E​​E​903  ​D​​S​​PTR​​V​​K​​R​​S​​Q​​G​​R​913  ​I​​P​​V​​K​​W​​M​​A​​I​​E​​S​923  ​L​​F​​D​​H​​I​​PTR​​T​​T​​Q​​S​933  ​D​​V​​W​​S​​F​​G​​V​​L​​L​​W​943  ​E​​I​​V​​T​​L​​G​​G​​N​​P​​Y​953  ​P​​G​​I​​P​​P​​E​​R​​L​​F​​N​963  ​L​​L​​K​​T​​G​​H​​R​​M​​E​​R​973  ​P​​D​​N​​C​​S​​E​​E​​M​​Y​​R​983  ​L​​M​​L​​Q​​C​​W​​K​​Q​​E​​P​993  ​D​​K​​R​​P​​V​​F​​A​​D​​I​​S​1003 ​K​​D​​L​​E​​K​​M​​M​​V​​K​​R​     ​R​
Type
Asm Id
Dynamic Bonds

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