Crystal structure of flurbiprofen bound to S121P murine COX-2 mutant

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RCSB PDB Mol* Viewer 2.10.6 [10/28/2024, 3:56:31 PM]
Sequence of
33   ​H​​H​​P​​C​​C​​S​​N​​P​​C​​Q​43   ​N​​R​​G​​E​​C​​M​​S​​T​​G​​F​53   ​D​​Q​​Y​​K​​C​​D​​C​​T​​R​​T​63   ​G​​F​​Y​​G​​E​​N​​C​​T​​T​​P​73   ​E​​F​​L​​T​​R​​I​​K​​L​​L​​L​83   ​K​​P​​T​​P​​N​​T​​V​​H​​Y​​I​93   ​L​​T​​H​​F​​K​​G​​V​​W​​N​​I​103  ​V​​N​​N​​I​​P​​F​​L​​R​​S​​L​113  ​I​​M​​K​​Y​​V​​L​​T​​S​​R​​P​123  ​Y​​L​​I​​D​​S​​P​​P​​T​​Y​​N​133  ​V​​H​​Y​​G​​Y​​K​​S​​W​​E​​A​143  ​F​​S​​N​​L​​S​​Y​​Y​​T​​R​​A​153  ​L​​P​​P​​V​​A​​D​​D​​C​​P​​T​163  ​P​​M​​G​​V​​K​​G​​N​​K​​E​​L​173  ​P​​D​​S​​K​​E​​V​​L​​E​​K​​V​183  ​L​​L​​R​​R​​E​​F​​I​​P​​D​​P​193  ​Q​​G​​S​​N​​M​​M​​F​​A​​F​​F​203  ​A​​Q​​H​​F​​T​​H​​Q​​F​​F​​K​213  ​T​​D​​H​​K​​R​​G​​P​​G​​F​​T​223  ​R​​G​​L​​G​​H​​G​​V​​D​​L​​N​233  ​H​​I​​Y​​G​​E​​T​​L​​D​​R​​Q​243  ​H​​K​​L​​R​​L​​F​​K​​D​​G​​K​253  ​L​​K​​Y​​Q​​V​​I​​G​​G​​E​​V​263  ​Y​​P​​P​​T​​V​​K​​D​​T​​Q​​V​273  ​E​​M​​I​​Y​​P​​P​​H​​I​​P​​E​283  ​N​​L​​Q​​F​​A​​V​​G​​Q​​E​​V​293  ​F​​G​​L​​V​​P​​G​​L​​M​​M​​Y​303  ​A​​T​​I​​W​​L​​R​​E​​H​​N​​R​313  ​V​​C​​D​​I​​L​​K​​Q​​E​​H​​P​323  ​E​​W​​G​​D​​E​​Q​​L​​F​​Q​​T​333  ​S​​R​​L​​I​​L​​I​​G​​E​​T​​I​343  ​K​​I​​V​​I​​E​​D​​Y​​V​​Q​​H​353  ​L​​S​​G​​Y​​H​​F​​K​​L​​K​​F​363  ​D​​P​​E​​L​​L​​F​​N​​Q​​Q​​F​373  ​Q​​Y​​Q​​N​​R​​I​​A​​S​​E​​F​383  ​N​​T​​L​​Y​​H​​W​​H​​P​​L​​L​393  ​P​​D​​T​​F​​N​​I​​E​​D​​Q​​E​403  ​Y​​S​​F​​K​​Q​​F​​L​​Y​​N​​N​413  ​S​​I​​L​​L​​E​​H​​G​​L​​T​​Q​423  ​F​​V​​E​​S​​F​​T​​R​​Q​​I​​A​433  ​G​​R​​V​​A​​G​​G​​R​​N​​V​​P​443  ​I​​A​​V​​Q​​A​​V​​A​​K​​A​​S​453  ​I​​D​​Q​​S​​R​​E​​M​​K​​Y​​Q​463  ​S​​L​​N​​E​​Y​​R​​K​​R​​F​​S​473  ​L​​K​​P​​Y​​T​​S​​F​​E​​E​​L​483  ​T​​G​​E​​K​​E​​M​​A​​A​​E​​L​493  ​K​​A​​L​​Y​​S​​D​​I​​D​​V​​M​503  ​E​​L​​Y​​P​​A​​L​​L​​V​​E​​K​513  ​P​​R​​P​​D​​A​​I​​F​​G​​E​​T​523  ​M​​V​​E​​L​​G​​A​​P​​F​​S​​L​533  ​K​​G​​L​​M​​G​​N​​P​​I​​C​​S​543  ​P​​Q​​Y​​W​​K​​P​​S​​T​​F​​G​553  ​G​​E​​V​​G​​F​​K​​I​​I​​N​​T​563  ​A​​S​​I​​Q​​S​​L​​I​​C​​N​​N​573  ​V​​K​​G​​C​​P​​F​​T​​S​​F​​N​583  ​V​​Q​
Type
Asm Id
Dynamic Bonds
Symmetry Index

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