5J7B | pdb_00005j7b

The identification and pharmacological characterization of 6-(tert-butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a highly potent and selective inhibitor of RIP2 Kinase, GSK583 complex

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RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
     ​M​​D​​Y​​K​​D​​D​​D​​D​​K​​E​     ​N​​L​​Y​​F​​Q​​G​​M​​N​​G​​E​5    ​A​​I​​C​​S​​A​​L​​P​​T​​I​​P​15   ​Y​​H​​K​​L​​A​​D​​L​​R​​Y​​L​25   ​S​​R​​G​​A​​S​​G​​T​​V​​S​​S​35   ​A​​R​​H​​A​​D​​W​​R​​V​​Q​​V​45   ​A​​V​​K​​H​​L​​H​​I​​H​​T​​P​55   ​L​​L​​D​​S​​E​​R​​K​​D​​V​​L​65   ​R​​E​​A​​E​​I​​L​​H​​K​​A​​R​75   ​F​​S​​Y​​I​​L​​P​​I​​L​​G​​I​85   ​C​​N​​E​​P​​E​​F​​L​​G​​I​​V​95   ​T​​E​​Y​​M​​P​​N​​G​​S​​L​​N​105  ​E​​L​​L​​H​​R​​K​​T​​E​​Y​​P​115  ​D​​V​​A​​W​​P​​L​​R​​F​​R​​I​125  ​L​​H​​E​​I​​A​​L​​G​​V​​N​​Y​135  ​L​​H​​N​​M​​T​​P​​P​​L​​L​​H​145  ​H​​D​​L​​K​​T​​Q​​N​​I​​L​​L​155  ​D​​N​​E​​F​​H​​V​​K​​I​​A​​D​165  ​F​​G​​L​​S​​K​​W​​R​​M​​M​​S​     ​L​​S​​Q​​S​​R​​S​​S​​K​​S​​A​     ​P​​E​​G​​G​​T​​I​​I​​Y​​M​​P​195  ​P​​E​​N​​Y​​E​​P​​G​​Q​​K​​S​205  ​R​​A​​S​​I​​K​​H​​D​​I​​Y​​S​215  ​Y​​A​​V​​I​​T​​W​​E​​V​​L​​S​225  ​R​​K​​Q​​P​​F​​E​​D​​V​​T​​N​235  ​P​​L​​Q​​I​​M​​Y​​S​​V​​S​​Q​245  ​G​​H​​R​​P​​V​​I​​N​​E​​E​​S​255  ​L​​P​​Y​​D​​I​​P​​H​​R​​A​​R​265  ​M​​I​​S​​L​​I​​E​​S​​G​​W​​A​275  ​Q​​N​​P​​D​​E​​R​​P​​S​​F​​L​285  ​K​​C​​L​​I​​E​​L​​E​​P​​V​​L​295  ​R​​T​​F​​E​​E​​I​​T​​F​​L​​E​305  ​A​​V​​I​​Q​​L​​K​
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Asm Id
Dynamic Bonds

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