3D View: 5ESM

Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) T322I mutant complexed with fluconazole

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RCSB PDB Mol* Viewer 2.10.6 [10/28/2024, 3:56:31 PM]
Sequence of
     ​M​​S​​A​​T​​K​​S​​I​​V​​G​​E​11   ​A​​L​​E​​Y​​V​​N​​I​​G​​L​​S​21   ​H​​F​​L​​A​​L​​P​​L​​A​​Q​​R​31   ​I​​S​​L​​I​​I​​I​​I​​P​​F​​I​41   ​Y​​N​​I​​V​​W​​Q​​L​​L​​Y​​S​51   ​L​​R​​K​​D​​R​​P​​P​​L​​V​​F​61   ​Y​​W​​I​​P​​W​​V​​G​​S​​A​​V​71   ​V​​Y​​G​​M​​K​​P​​Y​​E​​F​​F​81   ​E​​E​​C​​Q​​K​​K​​Y​​G​​D​​I​91   ​F​​S​​F​​V​​L​​L​​G​​R​​V​​M​101  ​T​​V​​Y​​L​​G​​P​​K​​G​​H​​E​111  ​F​​V​​F​​N​​A​​K​​L​​A​​D​​V​121  ​S​​A​​E​​A​​A​​Y​​A​​H​​L​​T​131  ​T​​P​​V​​F​​G​​K​​G​​V​​I​​Y​141  ​D​​C​​P​​N​​S​​R​​L​​M​​E​​Q​151  ​K​​K​​F​​V​​K​​G​​A​​L​​T​​K​161  ​E​​A​​F​​K​​S​​Y​​V​​P​​L​​I​171  ​A​​E​​E​​V​​Y​​K​​Y​​F​​R​​D​181  ​S​​K​​N​​F​​R​​L​​N​​E​​R​​T​191  ​T​​G​​T​​I​​D​​V​​M​​V​​T​​Q​201  ​P​​E​​M​​T​​I​​F​​T​​A​​S​​R​211  ​S​​L​​L​​G​​K​​E​​M​​R​​A​​K​221  ​L​​D​​T​​D​​F​​A​​Y​​L​​Y​​S​231  ​D​​L​​D​​K​​G​​F​​T​​P​​I​​N​241  ​F​​V​​F​​P​​N​​L​​P​​L​​E​​H​251  ​Y​​R​​K​​R​​D​​H​​A​​Q​​K​​A​261  ​I​​S​​G​​T​​Y​​M​​S​​L​​I​​K​271  ​E​​R​​R​​K​​N​​N​​D​​I​​Q​​D​281  ​R​​D​​L​​I​​D​​S​​L​​M​​K​​N​291  ​S​​T​​Y​​K​​D​​G​​V​​K​​M​​T​301  ​D​​Q​​E​​I​​A​​N​​L​​L​​I​​G​311  ​V​​L​​M​​G​​G​​Q​​H​​T​​S​​A​321  ​A​​I​​S​​A​​W​​I​​L​​L​​H​​L​331  ​A​​E​​R​​P​​D​​V​​Q​​Q​​E​​L​341  ​Y​​E​​E​​Q​​M​​R​​V​​L​​D​​G​351  ​G​​K​​K​​E​​L​​T​​Y​​D​​L​​L​361  ​Q​​E​​M​​P​​L​​L​​N​​Q​​T​​I​371  ​K​​E​​T​​L​​R​​M​​H​​H​​P​​L​381  ​H​​S​​L​​F​​R​​K​​V​​M​​K​​D​391  ​M​​H​​V​​P​​N​​T​​S​​Y​​V​​I​401  ​P​​A​​G​​Y​​H​​V​​L​​V​​S​​P​411  ​G​​Y​​T​​H​​L​​R​​D​​E​​Y​​F​421  ​P​​N​​A​​H​​Q​​F​​N​​I​​H​​R​431  ​W​​N​​N​​D​​S​​A​​S​​S​​Y​​S​441  ​V​​G​​E​​E​​V​​D​​Y​​G​​F​​G​451  ​A​​I​​S​​K​​G​​V​​S​​S​​P​​Y​461  ​L​​P​​F​​G​​G​​G​​R​​H​​R​​C​471  ​I​​G​​E​​H​​F​​A​​Y​​C​​Q​​L​481  ​G​​V​​L​​M​​S​​I​​F​​I​​R​​T​491  ​L​​K​​W​​H​​Y​​P​​E​​G​​K​​T​501  ​V​​P​​P​​P​​D​​F​​T​​S​​M​​V​511  ​T​​L​​P​​T​​G​​P​​A​​K​​I​​I​521  ​W​​E​​K​​R​​N​​P​​E​​Q​​K​​I​531  ​G​​G​​R​​H​​H​​H​​H​​H​​H​
Type
Asm Id
Dynamic Bonds

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