4JPG | pdb_00004jpg

2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as Novel PKM2 Activators

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RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
     ​G​​S​​M​​K​​H​​H​​H​​H​​H​​H​     ​D​​Y​​G​​I​​L​​T​​T​​E​​N​​L​     ​Y​​F​​Q​​G​​S​​M​​S​​K​​P​​H​     ​S​​E​​A​​G​​T​​A​​F​​I​​Q​​T​16   ​Q​​Q​​L​​H​​A​​A​​M​​A​​D​​T​26   ​F​​L​​E​​H​​M​​C​​R​​L​​D​​I​36   ​D​​S​​P​​P​​I​​T​​A​​R​​N​​T​46   ​G​​I​​I​​C​​T​​I​​G​​P​​A​​S​56   ​R​​S​​V​​E​​T​​L​​K​​E​​M​​I​66   ​K​​S​​G​​M​​N​​V​​A​​R​​L​​N​76   ​F​​S​​H​​G​​T​​H​​E​​Y​​H​​A​86   ​E​​T​​I​​K​​N​​V​​R​​T​​A​​T​96   ​E​​S​​F​​A​​S​​D​​P​​I​​L​​Y​106  ​R​​P​​V​​A​​V​​A​​L​​D​​T​​K​116  ​G​​P​​E​​I​​R​​T​​G​​L​​I​​K​126  ​G​​S​​G​​T​​A​​E​​V​​E​​L​​K​136  ​K​​G​​A​​T​​L​​K​​I​​T​​L​​D​146  ​N​​A​​Y​​M​​E​​K​​C​​D​​E​​N​156  ​I​​L​​W​​L​​D​​Y​​K​​N​​I​​C​166  ​K​​V​​V​​E​​V​​G​​S​​K​​I​​Y​176  ​V​​D​​D​​G​​L​​I​​S​​L​​Q​​V​186  ​K​​Q​​K​​G​​A​​D​​F​​L​​V​​T​196  ​E​​V​​E​​N​​G​​G​​S​​L​​G​​S​206  ​K​​K​​G​​V​​N​​L​​P​​G​​A​​A​216  ​V​​D​​L​​P​​A​​V​​S​​E​​K​​D​226  ​I​​Q​​D​​L​​K​​F​​G​​V​​E​​Q​236  ​D​​V​​D​​M​​V​​F​​A​​S​​F​​I​246  ​R​​K​​A​​S​​D​​V​​H​​E​​V​​R​256  ​K​​V​​L​​G​​E​​K​​G​​K​​N​​I​266  ​K​​I​​I​​S​​K​​I​​E​​N​​H​​E​276  ​G​​V​​R​​R​​F​​D​​E​​I​​L​​E​286  ​A​​S​​D​​G​​I​​M​​V​​A​​R​​G​296  ​D​​L​​G​​I​​E​​I​​P​​A​​E​​K​306  ​V​​F​​L​​A​​Q​​K​​M​​M​​I​​G​316  ​R​​C​​N​​R​​A​​G​​K​​P​​V​​I​326  ​C​​A​​T​​Q​​M​​L​​E​​S​​M​​I​336  ​K​​K​​P​​R​​P​​T​​R​​A​​E​​G​346  ​S​​D​​V​​A​​N​​A​​V​​L​​D​​G​356  ​A​​D​​C​​I​​M​​L​​S​​G​​E​​T​366  ​A​​K​​G​​D​​Y​​P​​L​​E​​A​​V​376  ​R​​M​​Q​​H​​L​​I​​A​​R​​E​​A​386  ​E​​A​​A​​I​​Y​​H​​L​​Q​​L​​F​396  ​E​​E​​L​​R​​R​​L​​A​​P​​I​​T​406  ​S​​D​​P​​T​​E​​A​​T​​A​​V​​G​416  ​A​​V​​E​​A​​S​​F​​K​​C​​C​​S​426  ​G​​A​​I​​I​​V​​L​​T​​K​​S​​G​436  ​R​​S​​A​​H​​Q​​V​​A​​R​​Y​​R​446  ​P​​R​​A​​P​​I​​I​​A​​V​​T​​R​456  ​N​​P​​Q​​T​​A​​R​​Q​​A​​H​​L​466  ​Y​​R​​G​​I​​F​​P​​V​​L​​C​​K​476  ​D​​P​​V​​Q​​E​​A​​W​​A​​E​​D​486  ​V​​D​​L​​R​​V​​N​​F​​A​​M​​N​496  ​V​​G​​K​​A​​R​​G​​F​​F​​K​​K​506  ​G​​D​​V​​V​​I​​V​​L​​T​​G​​W​516  ​R​​P​​G​​S​​G​​F​​T​​N​​T​​M​526  ​R​​V​​V​​P​​V​​P​
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Asm Id
Dynamic Bonds

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