4CQG | pdb_00004cqg

The crystal structure of MPK38 in complex with OTSSP167, an orally- administrative MELK selective inhibitor

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RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
     ​M​​K​​D​​Y​​D​​E​​L​​L​​K​​Y​11   ​Y​​E​​L​​Y​​E​​T​​I​​G​​T​​G​21   ​G​​F​​A​​K​​V​​K​​L​​A​​C​​H​31   ​V​​L​​T​​G​​E​​M​​V​​A​​I​​K​41   ​I​​M​​D​​K​​N​​A​​L​​G​​S​​D​51   ​L​​P​​R​​V​​K​​T​​E​​I​​D​​A​61   ​L​​K​​S​​L​​R​​H​​Q​​H​​I​​C​71   ​Q​​L​​Y​​H​​V​​L​​E​​T​​K​​N​81   ​K​​I​​F​​M​​V​​L​​E​​Y​​C​​P​91   ​G​​G​​E​​L​​F​​D​​Y​​I​​I​​S​101  ​Q​​D​​R​​L​​S​​E​​E​​E​​T​​R​111  ​V​​V​​F​​R​​Q​​I​​L​​S​​A​​V​121  ​A​​Y​​V​​H​​S​​Q​​G​​Y​​A​​H​131  ​R​​D​​L​​K​​P​​E​​N​​L​​L​​F​141  ​D​​E​​N​​H​​K​​L​​K​​L​​I​​D​151  ​F​​G​​L​​C​​A​​K​​P​​K​​G​​N​     ​K​​D​​Y​​H​​L​​Q​​E​​C​​C​​G​171  ​S​​L​​A​​Y​​A​​A​​P​​E​​L​​I​181  ​Q​​G​​K​​S​​Y​​L​​G​​S​​E​​A​191  ​D​​V​​W​​S​​M​​G​​I​​L​​L​​Y​201  ​V​​L​​M​​C​​G​​F​​L​​P​​F​​D​211  ​D​​D​​N​​V​​M​​A​​L​​Y​​K​​K​221  ​I​​M​​R​​G​​K​​Y​​E​​V​​P​​K​231  ​W​​L​​S​​P​​S​​S​​I​​L​​L​​L​241  ​Q​​Q​​M​​L​​Q​​V​​D​​P​​K​​K​251  ​R​​I​​S​​M​​R​​N​​L​​L​​N​​H​261  ​P​​W​​V​​M​​Q​​D​​Y​​S​​C​​P​271  ​V​​E​​W​​Q​​S​​K​​T​​P​​L​​T​281  ​H​​L​​D​​E​​D​​C​​V​​T​​E​​L​291  ​S​​V​​H​​H​​R​​S​​S​​R​​Q​​T​301  ​M​​E​​D​​L​​I​​S​​S​​W​​Q​​Y​311  ​D​​H​​L​​T​​A​​T​​Y​​L​​L​​L​321  ​L​​A​​K​​K​​A​​R​​L​​E​​H​​H​331  ​H​
Type
Asm Id
Dynamic Bonds

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