4C8B | pdb_00004c8b

Structure of the kinase domain of human RIPK2 in complex with ponatinib

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RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
     ​M​​G​​H​​H​​H​​H​​H​​H​​S​​S​     ​G​​V​​D​​L​​G​​T​​E​​N​​L​​Y​     ​F​​Q​​S​​M​​S​​A​​L​​P​​T​​I​14   ​P​​Y​​H​​K​​L​​A​​D​​L​​R​​Y​24   ​L​​S​​R​​G​​A​​S​​G​​T​​V​​S​34   ​S​​A​​R​​H​​A​​D​​W​​R​​V​​Q​44   ​V​​A​​V​​K​​H​​L​​H​​I​​H​​T​54   ​P​​L​​L​​D​​S​​E​​R​​K​​D​​V​64   ​L​​R​​E​​A​​E​​I​​L​​H​​K​​A​74   ​R​​F​​S​​Y​​I​​L​​P​​I​​L​​G​84   ​I​​C​​N​​E​​P​​E​​F​​L​​G​​I​94   ​V​​T​​E​​Y​​M​​P​​N​​G​​S​​L​104  ​N​​E​​L​​L​​H​​R​​K​​T​​E​​Y​114  ​P​​D​​V​​A​​W​​P​​L​​R​​F​​R​124  ​I​​L​​H​​E​​I​​A​​L​​G​​V​​N​134  ​Y​​L​​H​​N​​M​​T​​P​​P​​L​​L​144  ​H​​H​​D​​L​​K​​T​​Q​​N​​I​​L​154  ​L​​D​​N​​E​​F​​H​​V​​K​​I​​A​164  ​D​​F​​G​​L​​S​​K​​W​​C​​M​​M​     ​S​​L​​S​​Q​​S​​R​​S​​S​​K​​S​     ​A​​P​​E​​G​​G​​T​​I​​I​​Y​​M​194  ​P​​P​​E​​N​​Y​​E​​P​​G​​Q​​K​     ​S​​R​​A​​S​​I​​K​​H​​D​​I​​Y​214  ​S​​Y​​A​​V​​I​​T​​W​​E​​V​​L​224  ​S​​R​​K​​Q​​P​​F​​E​​D​​V​​T​234  ​N​​P​​L​​Q​​I​​M​​Y​​S​​V​​S​244  ​Q​​G​​H​​R​​P​​V​​I​​N​​E​​E​254  ​S​​L​​P​​Y​​D​​I​​P​​H​​R​​A​264  ​R​​M​​I​​S​​L​​I​​E​​S​​G​​W​274  ​A​​Q​​N​​P​​D​​E​​R​​P​​S​​F​284  ​L​​K​​C​​L​​I​​E​​L​​E​​P​​V​294  ​L​​R​​T​​F​​E​​E​​I​​T​​F​​L​304  ​E​​A​​V​​I​​Q​​L​​K​​K​​T​​K​314  ​L​​Q​​S​​V​
Type
Asm Id
Dynamic Bonds

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